Center of Excellence in Higher Education
The First Private University in Bangladesh

Dr. Ferdous Khan

Full-Time Faculty
Associate Professor

Ph.D., Tottori University, Japan

Phone: +880-2-55668200 Ext:
Email: khan.ferdous@northsouth.edu
Office: SAC 1014

Curriculum Vitae

 

Dr. Ferdous Khan received a PhD degree from The United Graduate School of Agricultural Sciences, Tottori University, Japan, under the supervision of Professor Dr. Kazushige Yokota. His doctoral study mainly focused on the molecular pharmacology and pathogenesis of obesity. His study involved extensive works on different cell lines as well as animal models like mice. His research theme was “Specific action of prostacyclin on adipogenesis at different stages of cultured adipocytes”. He revealed important roles of several transcription factors and bioactive lipids in the differentiaition and maturation of 3T3-L1 preadipocytes which would help in the drug discovery and development of diabetes resistance, obesity, hypertension and related metabolic disorders. Before going to Japan, Dr. Ferdous Khan completed BPharm and MPharm degrees from the University of Dhaka. During his MPharm, he secured first-class first position in the Department of Pharmaceutical Technology with the highest score in the Faculty of Pharmacy.

Now he is working as an associate professor in the Department of Pharmaceutical Sciences, North South University, Bangladesh. He also worked as a lecturer and assistant professor in the Department of Pharmacy of the State University of Bangladesh, ASA University Bangladesh, and Daffodil International University. Besides academia, he also worked at Beximco Pharmaceuticals Ltd. as a quality control officer.
  1. Alimullah M, Jahan I, Rahman, MM, Khan F, Ahmed KS, Hossain MH, Arabnozari H, Alam MA, Sarker SD, Nahar L & Subhan N. Camellia sinensis powder rich in epicatechin and polyphenols attenuates isoprenaline induced cardiac injury by activating the Nrf2 HO1 antioxidant pathway in rats. Sci Rep 15, 20859 (2025). https://doi.org/10.1038/s41598-025-08720
  2. Jahan I, Shuvo AU, Alimullah M, Rahman AN, Siddiqua S, Rafia S, Khan F, Ahmed KS, Hossain H, Akramuddaula K, Alam MA. Purple potato extract modulates fat metabolizing genes expression, prevents oxidative stress, hepatic steatosis, and attenuates high-fat diet-induced obesity in male rats. PloS one. 2025 Apr 1;20(4):e0318162.
  3. Shuvo AUH, Alimullah M, Jahan I, Mitu KF, Rahman MJ, Akramuddaula K, Khan F, Dash PR, Subhan N, Alam MA. Evaluation of Xanthine Oxidase Inhibitors Febuxostat and Allopurinol on Kidney Dysfunction and Histological Damage in Two-Kidney, One-Clip (2K1C) Rats. Scientifica (Cairo). 2025 Jan 22;2025:7932075. doi: 10.1155/sci5/7932075. PMID: 39886537; PMCID: PMC11779995.
  4. Zahan T, Alimullah M, Jahan I, Uddin MB, Akter KA, Rahman MJ, Siddiqua S, Ela KN, Amin S, Ahmed KS, Hossain H, Khan F, Alam MA, Subhan N, Baccaurea ramiflora fruit peel powder supplementation prevented inflammatory cell infiltration, oxidative stress, and fibrosis in carbon tetrachloride (CCl4) administered ovariectomized rats, Phytomedicine Plus, Volume 5, Issue 1, 2025, 100719, ISSN 2667-0313,https://doi.org/10.1016/j.phyplu.2024.100719.
  5. Rahman MM, Alimullah M, Yasmin T, Akhter N, Ahmed I, Khan F, Saha M, Halim MA, Subhan N, Haque MA, Alam MA. Cardioprotective action of apocynin in isoproterenol-induced cardiac damage is mediated through Nrf-2/HO-1 signaling pathway. Food Science and Nutrition. 2024
  6. Alimullah, M., Rahman, N., Sornaker, P., Akramuddaula, K., Sarif, S., Siddiqua, S., Mitu, K. F., Jahan, I., Khan, F., Subhan, N., & Alam, M. A. Evaluation of Terminalia arjuna Bark Powder Supplementation on Isoprenaline-Induced Oxidative Stress and Inflammation in the Heart of Long Evans Rats, Understanding the Molecular Mechanism of This Old Medicinal Plant. Journal of Medicinal Natural Products. 2024. doi: Retrieved from https://www.sciltp.com/journals/jmnp/article/view/493
  7. Mitu MM, Toma TR, Nesa F, Rumpa FT, Khan F, Akter KA, Uddin KN, Shohag MH. Analysis of genetic association of vitamin D receptor (VDR) gene FokI polymorphism in Bangladeshi patients with type 2 diabetes mellitus. Gene. 2024 Dec 20;930:148863. doi: 10.1016/j.gene.2024.148863. Epub 2024 Aug 15. PMID: 39153706.
  8. Khan, S. I., Karim, R., Khan, S. I., Chowdhury, M. A. K., Shill, M. C., Pasha, F. M., MS Shohag, M. S., Khan, F., Reza, H. M. (2024). Factors affecting severity and prognosis of traumatic brain injury among Bangladeshi patients: An institution based cross-sectional study. Traffic Injury Prevention, 1–9. https://doi.org/10.1080/15389588.2024.2363470
  9. Alimullah M, Shuvo AUH, Jahan I, Ismail IN, Islam SMM, Sultana M, Saad MR, Raihan S, Khan F, Alam MA, Subhan N. Evaluation of the modulating effect of epidermal growth factor receptor inhibitor cetuximab in carbon-tetrachloride induce hepatic fibrosis in rats. Biochem Biophys Rep. 2024 Mar 21;38:101689. doi: 10.1016/j.bbrep.2024.101689. PMID: 38560050; PMCID: PMC10979143.
  10. Tammana TC, Sumaia S, Ishrat J, Iffat NI, Faizul IC, Siddiqua S, Tahmina Y, Nurul MI, Khan F, Nusrat S, Alam MA. Protective effects of l-carnitine on isoprenaline -induced heart and kidney dysfunctions: Modulation of inflammation and oxidative stress-related gene expression in rats, Heliyon, Volume 10, Issue 3, 2024, e25057, ISSN 2405-8440, https://doi.org/10.1016/j.heliyon.2024.e25057.
  11. Syed Abdul Kuddus, Afsana Alam, Abdullah Md. Sifat, Tasmi Tamanna, Shaiful Alam, Farjana Abedin, Reatul Karim, Md. Zakir Sultan, Khan F. Effect of polymer concentration on the release of naproxen from enteric coated sustained release tablets. J. Bio. Exp. Pharm 2023, 1:70–90
  12. Jahan I, Saha P, Eysha Chisty TT, Mitu KF, Chowdhury FI, Ahmed KS, Hossain H, Khan F, Subhan N, Alam MA. Crataeva nurvala Bark (Capparidaceae) Extract Modulates Oxidative Stress-Related Gene Expression, Restores Antioxidant Enzymes, and Prevents Oxidative Stress in the Kidney and Heart of 2K1C Rats. Evid Based Complement Alternat Med. 2023 Aug 9;2023:4720727. doi: 10.1155/2023/4720727. PMID: 37593003; PMCID: PMC10432060.
  13. Jahan I, Islam MD, Sarif S, Amena IJ, Shuvo AUH, Akter N, Chowdhury FI, Akter R, Ahmed I, Khan F, et al. Tempol Alters Antioxidant Enzyme Function, Modulates Multiple Genes Expression, and Ameliorates Hepatic and Renal Impairment in Carbon Tetrachloride (CCl4)-Intoxicated Rats. Livers. 2023; 3(1):105-120. https://doi.org/10.3390/livers3010010.
  14. Chowdhury FI, Yasmin T, Akter R, Islam MN, Hossain MM, Khan F, Aldhahrani A, Soliman MM, Subhan N, Haque MA, Alam MA. Resveratrol treatment modulates several antioxidant and anti-inflammatory genes expression and ameliorated oxidative stress mediated fibrosis in the kidneys of high-fat diet-fed rats. Saudi Pharm J. 2022 Oct;30(10):1454-1463. doi: 10.1016/j.jsps.2022.07.006. Epub 2022 Jul 25. PMID: 36387333; PMCID: PMC9649349.
  15. Yasmin T, Rahman MM, Khan F, Kabir F, Nahar K, Lasker S, Islam MD, Hossain MM, Hasan R, Rana S and Alam MA (2021) High fat diet-induced non-alcoholic fatty liver and dyslipidemia was ameliorated by metformin treatment, which also modulates antioxidant genes by Nrf-2-HO mediated pathway in rats. Biochemistry and Biophysics Reports, 28:101168.
  16. Selim S, Akter N, Nayan SI, Chowdhury FI, Saffoon N, Khan F, Ahmed KS, Ahmed MI, Hossain MM, Alam MA. Flacourtia indica fruit extract modulated antioxidant gene expression, prevented oxidative stress and ameliorated kidney dysfunction in isoprenaline administered rats. Biochem Biophys Rep. 2021 May 18;26:101012. doi: 10.1016/j.bbrep.2021.101012. PMID: 34041370; PMCID: PMC8142055.
  17. Miah P, Mohona SBS, Rahman MM, Subhan N, Khan F, Hossain H, Sharker SM, Alam MA. Supplementation of cumin seed powder prevents oxidative stress, hyperlipidemia and non-alcoholic fatty liver in high fat diet fed rats. Biomed Pharmacother. 2021 Jul 10;141:111908. doi: 10.1016/j.biopha.2021.111908. Epub ahead of print. PMID: 34328087.
  18. Nayan SI, Chowdhury FI, Akter N, Rahman MN, Selim S, Saffoon N, Khan F, Subhan N, Hossain M, Ahmed KS, Hossain H, Haque MA, Alam MA (2021) Leaf powder supplementation of Senna alexandrina ameliorates oxidative stress, inflammation, and hepatic steatosis in high-fat diet-fed obese rats. PLoS ONE 16(4): e0250261. https://doi.org/10.1371/journal.pone.0250261.
  19. Alam MA, Islam P, Subhan N, Rahman MM, Khan F, Burrows GE, Nahar L, Sarker SD. Potential health benefits of anthocyanins in oxidative stress related disorders Phytochemistry Reviews (IF 4.298) Pub Date: 2021-05-08 , DOI: 10.1007/s11101-021-09757-1.
  20. Akter N, Chowdhury FI, Selim S, Nayan SI, Khan F, Subhan F, Hossain H, Rahman MM, Haque MA, Alam MA. Polyphenolics in ramontchi protect cardiac tissues via suppressing isoprenaline-induced oxidative stress and inflammatory responses in Long-Evans rats. Journal of Functional Foods. 75, (2020), 104250. https://doi.org/10.1016/j.jff.2020.104250.
  21. Kuddus SA, Bhuiyan MI, Subhan N, Shohag MH, Rahman A, Hossain MM, Alam MA and Khan F. Antioxidant-rich Tamarindus indica leaf extract reduced high-fat diet-induced obesity in rat through modulation of gene expression. Clinical Phytoscience 6, 68 (2020). https://doi.org/10.1186/s40816-020-00213-9.
  22. Hasan R, Lasker S, Hasan A, Zerin F, Zamila M, Parvez F, Rahman MM, Khan F, Subhan N, Alam MA. Canagliflozin ameliorates renal oxidative stress and inflammation by stimulating AMPK–Akt–eNOS pathway in the isoprenaline-induced oxidative stress model. Sci Rep 10, 14659 (2020). https://doi.org/10.1038/s41598-020-71599-2.
  23. Hasan R, Lasker S, Hasan A, Zerin F, Zamila M, Chowdhury FI, Nayan SI, Rahman MM, Khan F, Subhan N, Alam MA. Canagliflozin attenuates isoprenaline-induced cardiac oxidative stress by stimulating multiple antioxidant and anti-inflammatory signaling pathways. Sci Rep 10, 14459 (2020). https://doi.org/10.1038/s41598-020-71449-1.
  24. Kuddus SA, Tasnim Z, Shohag MH, Yasmin T, Uddin MS, Hossain MM, Subhan N, Alam MA, Khan F. “Dillenia indica fruit extract suppressed diet-induced obesity in rat by down-regulating the mRNA level of proadipogenic transcription factors and lipid metabolizing enzymes”, Current Nutrition & Food Science (2020) 16: 1. Published online (ready for print). https://doi.org/10.2174/1573401316999200901173319.
  25. Mamun F, Lasker S, Khan F, Yasmin T, Akter KA, Subhan N, Alam MA. Etoricoxib treatment prevented body weight gain and ameliorated oxidative stress in the liver of high-fat diet-fed rats 2020. Naunyn Schmiedebergs Arch Pharmacol. 2020;10.1007/s00210-020-01960-9. doi:10.1007/s00210-020-01960-9.
  26. Khan F, Kuddus SA, Shohag MH, Reza MH, Hossain M. Astaxanthin, the natural antioxidant, reduces reserpine induced depression in mice. Current Bioactive Compounds. (2020) 16: 1319. https://doi.org/10.2174/1573407216666200203142722.
  27. Golam K, Palash K, Shahid MS, Abhijit D, Hasanuzzaman M, Khan F, Rafiquzzaman M, Islam MS. 2017. Comparative study of antidiabetic effect of some selected plants extract from Cucurbitaceae family in alloxan-induced diabetic mice. Journal of Noakhali Science and Technology University (JNSTU), 1(2):9-18.
  28. Khan F, Syeda PK, Nartey MN, Rahman MS, Islam MS, Nishimura K, Jisaka M, Shono F, Yokota K. 2016. Pretreatment of cultured preadipocytes with arachidonic acid during the differentiation phase without a cAMP-elevating agent enhances fat storage after the maturation phase. Prostaglandins Other Lipid Mediat. 123(27):16-27.
  29. Khan F, Syeda PK, Nartey MN, Rahman MS, Islam MS, Nishimura K, Jisaka M, Shono F, Yokota K. 2016. Stimulation of fat storage by prostacyclin and selective agonists of prostanoid IP receptor during the maturation phase of cultured adipocytes. Cytotechnology 68(6):2417-2429.
  30. Rahman MS, Khan F, Syeda PK, Nishimura K, Jisaka M, Nagaya T, Shono F, Yokota 2014. Endogenous synthesis of prostacyclin was positively regulated during the maturation phase of cultured adipocytes. Cytotechnology 66(4):635-46.
  31. Rahman MS, Syeda PK, Khan F, Nishimura K, Jisaka M, Nagaya T, Shono F, Yokota K. 2013. Cultured preadipocytes undergoing stable transfection with cyclooxygenase-1 in the antisense direction accelerate adipogenesis during the maturation phase of adipocytes. Appl Biochem Biotechnol. 171(1):128-44.
  32. Syeda PK, Hossain MS, Chowdhury AA, Rahman MS, Khan F, Nishimura K, Jisaka M, Nagaya T, Shono F, Yokota K. 2012. A monoclonal antibody specific for Δ12-prostaglandin J2 and its utilization in the immunological assay in cell culture system of adipocytes. Hybridoma (Larchmt). 31(5):364-71.
  33. Shaikhul Millat Ibn Razzak, Khan F, Masuma Hossain, Tasmia Anika and Shamsad Afreen Moon, 2012. Impact of Sodium Lauryl Sulphate on the Release of Carbamazepine from Methocel K15M CR based Matrix Tablets. Bangladesh Pharmaceutical Journal. 15(1): 79-82.
  34. Khan F, Razzak, MSMI, Khan, M.Z.R., Azad, M.A.K., Chowdhury, J.A. and Reza, M.S. 2009. Theophylline Loaded Gastroretentive Floating Tablets Based on Hydrophilic Polymers: Preparation and in vitro Pakistan Journal of Pharmaceutical Sciences. 22 (2): 155-161.
  35. Razzak, M.S.M.I., Khan, F., Hossain, M., Khan, M.Z.R., Azad, M.A.K., and Reza, M.S. 2009. Effect of Channeling Agents on the Release Pattern of Theophylline from Kollidon SR Based Matrix Tablets. Pakistan Journal of Pharmaceutical Sciences. 22(3): 303-307.
  36. Khan, F., Razzak, M.S.M.I., Khan, M.Z.R., Azam, K.R., Sadat, S.M.A. and Reza, M.S. 2008. “Preparation and In vitro Evaluation of Theophylline Loaded Gastroretentive Floating Tablets of METHOCEL K4M”, The Dhaka University Journal of Pharmaceutical Sciences. 7(1): 65-70.
  37. Razzak, M.S.M.I., Khan, F., Khan, M.Z.R., Fatema, K., Islam, M.S. and Reza, M.S. 2008. “Effect of Channeling Agents on the Release Profile of Theophylline from METHOCEL K4M Based Matrix tablets” The Dhaka University Journal of Pharmaceutical Sciences 7(1): 27-32.
  38. Azam, K.R., Razzak, M.S.M.I., Khan, F., Islam, M.S., Rony, M.R. and Reza, M.S. 2008. Impact of Granulation Technique and Effect of Polymers on Theophylline Release from Matrix Tablets. The Dhaka University Journal of Pharmaceutical Sciences. 7(2): 133-139.
  39. Khan F, Younus Patoare, Pinky Karim, Mohiuddin Abdul Quadir, Israt Rayhan and Abul Hasnat, 2005. Effect of magnesium and zinc on the antimicrobial activities of some antibiotics against different strains of microorganism. Pakistan Journal of Pharmaceutical Sci 18(4): 57-61.
  1. Received Japanese Government Monbukagakusho Scholarship (MEXT) from October 2011 to September 2014 for pursuing a PhD as a graduate student of The United Graduate School of Agricultural Sciences, Tottori University, Japan.
  2. Became summa cum laude in the Master of Pharmaceutical Technology examination of the year 2002 (held in 2006) from the Department of Pharmaceutical Technology, University of Dhaka, Bangladesh.
  3. Received elementary school level, junior high school level, and secondary scholarships. 

Ph.D.

  • Awarded on 16th September 2016
  • From The United Graduate School of Agricultural Sciences, Tottori University, Japan
  • Subject of the Thesis: Specific action of prostacyclin on adipogenesis at different stages of cultured adipocytes
  • Major Contribution: Proposed a new mechanism of adipogenesis which can be considered for drug development

 M. Pharm.:

  • Completed M. Pharm. from the Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Dhaka in the year 2002 (held in 2006) with first class first position.

B. Pharm.:

  • Completed B. Pharm. From the Faculty of Pharmacy, University of Dhaka, in the year 2001 (held in 2004) with first-class eleventh position.

Higher Secondary School Certificate (HSC) Examination:

  • Passed from Dhaka College, Dhaka, under Dhaka Board in the year of 1997 (Science Group) with first division.

Secondary School Certificate (SSC) Examination:

  • Passed from Goila High School, Barisal, under Jessore Board in the year 1994 (Science Group) with first division.
  1. Currently, he is working as an associate professor in the Department of Pharmaceutical Sciences under the School of Health and Life Sciences, North South University, Bangladesh.
  1. He worked as an assistant professor in the Department of Pharmacy, Daffodil International University, from 2 May 2015 to 19 July 2016. He performed the responsibility of Head (In Charge) from 29 September 2015 to 19 July 2016 before joining NSU.
  2. He served as an assistant professor in the Department of Pharmacy, ASA University Bangladesh, on 1st February 2011 and worked until 30th September 2011 before going to Japan as a graduate student of the doctoral program of the United Graduate School of Agricultural Sciences, Tottori University.
  3. He was appointed as a lecturer in the Department of Pharmacy, State University of Bangladesh, on 2nd July 2005 and was promoted to assistant professor on 1st March 2010. I worked as an assistant professor in the Department of Pharmacy, State University of Bangladesh, until 31st January 2011.
  • He worked as a quality control officer at Beximco Pharmaceuticals Ltd., the 2nd largest pharmaceutical company in Bangladesh, from 19th August 2004 to 1st July 2005.
  • Clinical Toxicology and Safety Pharmacology
  • Advanced Pharmacology
  • Pathology and Toxicology
  • Pharmaceutical Microbiology
  • Human Physiology and Anatomy
  • Biopharmaceutics and Pharmacokinetics
  • Molecular Biology and Biochemistry
  • Executive Editor, Journal of Biosciences and Experimental Pharmacology
  • Editorial Board member, International Journal of Applied Research
  • Member, Japanese Universities Alumni Association in Bangladesh (JUAAB)
  • Member, Bangladesh Pharmaceutical Society (BPS)
  • Member, Pharmacy Graduates Association (PGA), Bangladesh

Now, Dr. Khan is interested in exploring the genetic background of hyperlipidemia and adipogenesis. More specifically, how different types of bioactive lipids and food ingredients can alter the expression of pro-adipogenic and anti-adipogenic genes. In this way he would like to shed some light on the ongoing stride to understand obesity and related disorders, which ultimately cause metabolic syndrome: the greatest threat to humankind.