| Full Time Faculty Professor Ph.D., University of Houston College of Pharmacy, USA Phone: +880-2-55668200 Ext: 1956 Google scholar link: https://scholar.google.com/citations?hl=en&user=Ca8V-8oAAAAJ
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A BRIEF BIOGRAPHY OF DR. G. M. SAYEDUR RAHMAN
Dr. G. M. Sayedur Rahman was born in November 07, 1973 in his maternal grandfather’s home in Khulna, a southern district in Bangladesh. His father was an official serving in the capacity of a director in Dhaka University, country’s pioneering and leading university. His father was the director of the Physical Education Department in the university. Dr. Rahman passed most of his childhood time in the Dhaka University campus. He used to live in the university residence because of his father’s work at the university. Dr. Rahman’s home schooling started under his mother’s supervision until Dr. Rahman attended the formal Schooling. After the completion of secondary level and higher secondary level of education (SSC-1988 & HSC-1990) from the University Laboratory School & College (under the Institution of Education & Learning, Dhaka University), Mr. Rahman decided to pursue his further higher education in biological sciences. The rich environment of learning and vibrant cultural heritage of the university paved Dr Rahman’s future path to higher education. Eventually, he got admitted in the Pharmacy Department in Dhaka University. He obtained first classes both in BPharm (1993) and in MPharm (1994). He obtained numerous scholarships and fellowships for his exceptional results in both bachelor and master.
After completion of Master degree, he joined in Eskayef Pharma ltd. (former SK&F Pharma Ltd.) as a Quality Control officer in Sept. 1997 and continued for one year until he joined in Khulna University (Sept. 1998). Dr. Rahman served as a young lecturer in the Pharmacy Discipline of Khulna University for three years (1998-2001). Later that year Dr. Rahman came back in Department of Pharmacy, Dhaka University and admitted in the M.Phil. program. In the mean time Dr. Rahman joined (2001) as an Assistant Professor in Northern University Bangladesh (NUB), a private university and served as the founding Chair for the Department of Pharmacy. He stayed in the NUB as both Full time and Part time faculty, until he left (Nov. 2006) for his PhD study in University of Houston College of Pharmacy (UHCOP), Houston, TX. Dr. Rahman obtained a six (6) years PhD (2007-2012) from UHCOP. He attended for a two years Post-Doctoral Training in MD Anderson Cancer Center, University of Texas, Houston, TX. After completion of the PostDoc, NSU authority offered him a position of Assistant Professor in the Dept. of Pharmaceutical Sciences. Dr. Rahman joined NSU (Sept. 29, 2014-present) and as of now he is serving.
In his personal life Dr. Rahman is married and father of a son. Mrs. Rahman stays at home and used do the home schooling to his son until, Farzad Rahman (his son) started going to school. Mr. Rahman is an avid reader and involved with charity and some social service works. Most of the leisure time, Dr. Rahman uses for reading books and scriptures and sciences. He is an occasional traveler. Recently Dr. Rahman got interested about AI, machine learning, social media BOTs etc. He is trying to incorporate AI in the computer aided drug design, which Dr. Rahman has been doing for last ten years.
RESEARCH PUBLICATIONS AFFILIATED WITH NSU:
1) Hossain, N., Shabnam, S., Emran, T., Zahid, Z. I., Alam, S., Bepari, A. K., Sayedur Rahman, G. M., & Reza, H. M. (2025). Coenzyme Q10 alleviates oxidative stress, inflammation and fibrosis via activation of TGFβ1/TNF-α in FCA-Salt hypertensive rats. Archives of Biochemistry and Biophysics, 769, 110444. https://doi.org/10.1016/j.abb.2025.110444
2) Sarker, M., Chowdhury, N., Bristy, A. T., Emran, T., Karim, R., Ahmed, R., Shaki, M. M., Sharkar, S. M., Sayedur Rahman, G. M., & Reza, H. M. (2024). Astaxanthin protects fludrocortisone acetate-induced cardiac injury by attenuating oxidative stress, fibrosis, and inflammation through TGF-β/Smad signaling pathway. Biomedicine & Pharmacotherapy, 181, 117703. https://doi.org/10.1016/j.biopha.2024.117703
3) Bepari, A. K., Takebayashi, H., Namme, J. N., Rahman, G. M. S., & Reza, H. M. (2023). A computational study to target necroptosis via RIPK1 inhibition. Journal of Biomolecular Structure and Dynamics, 41(14), 6502–6517. https://doi.org/10.1080/07391102.2022.2108900
4) Hossain, M., Suchi, T. T., Samiha, F., Islam, M. M. M., Tully, F. A., Hasan, J., Rahman, M. A., Shill, M. C., Bepari, A. K., Rahman, G. M. S., & Reza, H. M. (2023). Coenzyme Q10 ameliorates carbofuran induced hepatotoxicity and nephrotoxicity in wister rats. Heliyon, 9(2), e13727. https://doi.org/10.1016/j.heliyon.2023.e13727
5) Shill, M. C., Mohsin, M. N. A. B., Showdagor, U., Hasan, S. N., Zahid, M. Z. I., Khan, S. I., Hossain, M., Rahman, G. M. S., & Reza, H. M. (2023). Microbial sensitivity of the common pathogens for UTIs are declining in diabetic patients compared to non-diabetic patients in Bangladesh: An institution-based retrospective study. Heliyon, 9(1), e12897.
https://doi.org/10.1016/j.heliyon.2023.e12897
6) Rahman, M. A., Shuvo, A. A., Bepari, A. K., Hasan Apu, M., Shill, M. C., Hossain, M., Uddin, M., Islam, M. R., Bakshi, M. K., Hasan, J., Rahman, A., Rahman, G. M. S., & Reza, H. M. (2022). Curcumin improves D-galactose and normal-aging associated memory impairment in mice: In vivo and in silico-based studies. PLOS ONE, 17(6), e0270123.
https://doi.org/10.1371/journal.pone.0270123
7) Mostaid, M. S., Mumu, S. B., Haque, M. A., Sharmin, S., Jamiruddin, M. R., Sayedur Rahman, G. M., & Reza, H. M. (2021). Elevated serum expression of p53 and association of TP53 codon 72 polymorphisms with risk of cervical cancer in Bangladeshi women. PLOS ONE, 16(12), e0261984. https://doi.org/10.1371/journal.pone.0261984
8) Rahman, M. A., Shanjana, Y., Tushar, M. I., Mahmud, T., Rahman, G. M. S., Milan, Z. H., Sultana, T., Chowdhury, A. M. L. H., Bhuiyan, M. A., Islam, M. R., & Reza, H. M. (2021). Hematological abnormalities and comorbidities are associated with COVID-19 severity among hospitalized patients: Experience from Bangladesh. PLOS ONE, 16(7), e0255379. https://doi.org/10.1371/journal.pone.0255379
9) Emran, T., Chowdhury, N. I., Sarker, M., Bepari, A. K., Hossain, M., Rahman, G. M. S., & Reza, H. M. (2021). L-carnitine protects cardiac damage by reducing oxidative stress and inflammatory response via inhibition of tumor necrosis factor-alpha and interleukin-1beta against isoproterenol-induced myocardial infarction. Biomedicine & Pharmacotherapy, 143, 112139. https://doi.org/10.1016/j.biopha.2021.112139
10) Shill, M. C., Bepari, A. K., Khan, M., Tasneem, Z., Ahmed, T., Hasan, M. A., Alam, M. J., Hossain, M., Rahman, M. A., Sharker, S. M., Shahriar, M., Rahman, G. M. S., & Reza, H. M. (2021). Therapeutic potentials of Colocasia affinis leaf extract for the alleviation of streptozotocin-induced diabetes and diabetic complications: In vivo and in silico-based studies. Journal of Inflammation Research, 14, 443–459. https://doi.org/10.2147/JIR.S297348
11) Akash, S. Z., Lucky, F. Y., Hossain, M., Bepari, A. K., Rahman, G. M. S., Reza, H. M., & Sharker, S. M. (2021). Remote temperature-responsive parafilm dermal patch for on-demand topical drug delivery. Micromachines, 12(8), 975. https://doi.org/10.3390/mi12080975
12) Mithun Saha, Diti Rani Saha, Tahamina Ulhosna, Shazid Md Sharker, Md Hasanuzzaman Shohag, Muhammad Saiful Islam, Swapan K. Ray, G.M. Sayedur Rahman, Hasan Mahmud Reza (2021). QbD based development of resveratrol-loaded mucoadhesive lecithin/chitosan nanoparticles for prolonged ocular drug delivery, Journal of Drug Delivery Science and Technology, Volume 63, 2021, 102480, ISSN 1773-2247, https://doi.org/10.1016/j.jddst.2021.102480.
13) Reza, H. M., Saleh, R., Jain, P., Rahman, G. M. S., & Bepari, A. K. (2020). C-MAF expression in adult human ocular surface and its implication in pterygium pathogenesis. Reports of Biochemistry and Molecular Biology, 8(4), 419–423. https://doi.org/10.52547/biochem.8.4.419
14) Alam, Rafat & Rahman, GM Sayedur & Hasan, Nahid & Chowdhury, Abu Sayeed. (2020). A De-Novo drug design and ADMET study to design small molecule stabilizers targeting mutant (V210I) human prion protein against familial Creutzfeldt-Jakob disease (fCJD). International Journal of Computational Biology and Drug Design. 13. 21. 10.1504/IJCBDD.2020.105103
15) Nahar, K., Kabir, F., Islam, P., Rahman, M. M., Al Mamun, M. A., Faruk, M., Subhan, N., Rahman, G. M. S., Reza, H. M., & Alam, M. A. (2018). Cardioprotective effect of Amaranthus tricolor extract in isoprenaline induced myocardial damage in ovariectomized rats. Biomedicine & Pharmacotherapy, 103, 1154–1162. https://doi.org/10.1016/j.biopha.2018.04.151
16) Md Ashraful Alam, Abu Taher Sagor, Nabila Tabassum, Anayt Ulla, Manik Chandra Shill, Ghazi Muhammad Sayedur Rahman, Hemayet Hossain, Hasan Mahmud Reza (2018). Caffeic acid rich Citrus macroptera peel powder supplementation prevented oxidative stress, fibrosis and hepatic damage in CCl4 treated rats, Vol. 4, no. 1,pp. 1 – 10. https://doi.org/10.1186/s40816-018-0074-y
17) Sharker, S. M., Alam, M. A., Shill, M. C., Rahman, G. M. S., & Reza, H. M. (2017). Functionalized hBN as targeted photothermal chemotherapy for complete eradication of cancer cells. International Journal of Pharmaceutics, 534(1–2), 206–212. https://doi.org/10.1016/j.ijpharm.2017.10.025
18) Ulla, A., Mohamed, M. K., Sikder, B., Rahman, A. T., Sumi, F. A., Hossain, M., Reza, H. M., Rahman, G. M. S., & Alam, M. A. (2017). Coenzyme Q10 prevents oxidative stress and fibrosis in isoprenaline induced cardiac remodeling in aged rats. BMC Pharmacology and Toxicology, 18(1), 29. https://doi.org/10.1186/s40360-017-0136-7
19) Qasim R., Rahman G. M., Hasan N., M. Hossain M. S. (2017) An In-Silico Pharmacophore Based Anti-viral drug development for hepatitis C virus, International Journal of Pharmacological and Pharmaceutical Sciences. Vol: 4, No: 2.
POSTERS AND PODIUM PRESENTATIONS IN CONFERENCES/ PROFESSIONAL MEETINGS
1) Shahriar Alam Shanto, Sohag Mollah, Anika Tasnim Rodela, Md. Ariful Islam, G. M. Sayedur Rahman, In Silico development of novel anti-Parkinson’s drug candidate by targeting BCL2-associated athanogene 5 (BAG2), poster presentation at the 2nd Annual ICGNB 2022, NSU, Dhaka.
2) Farha-Al-Humaira, Faria Mahjabin Shupti, Md. Ariful Islam, G. M. Sayedur Rahman, In Silico drug design of the Cadherin-22 inhibitor as a potential treatment option for Cancer, poster presentation at the 2nd Annual ICGNB 2022, NSU, Dhaka.
3) Md. Abul Hasan Roni, Golam Mortuza, Ajoy Kumar, Suvro Biswas, Md. Abu Saleh, Shirmin Islam, G. M. Sayedur Rahman, Drug Discovery for Novel Coronavirus from natural compounds: Study with Artificial Intelligence and Molecular Dynamics, poster presentation at the 2nd Annual ICGNB 2022, NSU, Dhaka.
4) Ushashee Islam Paushee, Tasnim Tamanna, Rabiba Taher Mimra, G. M. Sayedur Rahman, Md. Ariful Islam, In Silico designing of a de novo REDD1 inhibitor for mitigating endothelial cell injury, poster presentation at the 2nd Annual ICGNB 2022, NSU, Dhaka.
5) Jannatun Nayem, Hasan Mahmud Reza, G. M. Sayedur Rahman, Asim Kumar Bepari. In Silico prediction of high risk pathogenic nsSNPs in the human ADAM10 gene, poster presentation at the 2nd Annual ICGNB 2022, NSU, Dhaka.
6) Sohag Mollah, Anika Tasnim Rodela, Shahriar Alam Shanto, G. M. Sayedur Rahman, Md. Ariful Islam, Computer aided drug design against asparagine endopeptidase (AEP) as a treatment option for Alzheimer’s disease (AD), poster presentation at the 2nd Annual ICGNB 2022, NSU, Dhaka.
7) Rabiba Taher Mimra, Sohag Mollah, Shahriar Alam Shanto, Md. Ariful Islam, G. M. Sayedur Rahman, Ushashee Islam Poushee, Tasnim Tamanna, In Silico drug design against pyruvate kinase M2 (PKM2) as a treatment approach for cancer, poster presentation at the 2nd Annual ICGNB 2022, NSU, Dhaka.
8) Azmy Mohammad Sayed, Asim Kumar Bepari, G. M. Sayedur Rahman, A de novo drug design approach to identify a potentially bioavailable PIM1 inhibitor, poster presentation at the 2nd Annual ICGNB 2022, NSU, Dhaka.
9) Anika Tasnim Rodela, Nasim Chowdhury, Miftahul Jannat, Md. Ariful Islam, G. M. Sayedur Rahman. Arg10 showed potential drug like properties targeting Ubiquitin carboxyl-terminal hydrolase 16 (USP16) in prostate cancer: a computer aid drug design model, poster presentation at the 2nd Annual ICGNB 2022, NSU, Dhaka.
10) Md. Fahim Akter, G. M. Sayedur Rahman, Hasan Mahmud Reza, 3D Structure Determination Of The NOX-1 And NOX-3 Enzyme (NADPH Oxidase) As Targets For The Future Development of New Atherosclerotic Drugs, poster presentation at the 1st Annual ICGNB 2017, NSU, Dhaka.
11) Md. Golam Mortuza, Abdulla Al Hasan, G. M. Sayedur Rahman, A. T. M. Zafrul Azam, STRUCTURE BASED DESIGN OF INHIBITORS OF SRPK1, poster presentation at the 1st Annual ICGNB 2017, NSU, Dhaka.
12) Nabila Tazneen, G. M. Sayedur Rahman, Hasan Mahmud Reza, In Silico Inhibitor Designing Against GSK3A Protein; A New Approach In Alzheimer Disease Management, poster presentation at the 1st Annual ICGNB 2017, NSU, Dhaka.
13) Rabeya Binte Haqaue, G. M. Sayedur Rahman, In Silico Inhibitor Designing Against Γ-Secretase Enzyme; A New Approach In Alzheimer Disease Management, poster presentation at the 1st Annual ICGNB 2017, NSU, Dhaka.
14) Romasa Qasim, G. M. Sayedur Rahman, Nahid Hasan, Sazzad Hossain, In Silico DISCOVERY OF POTENTIAL INHIBITOR AGAINST NS5B POLYMERASE OF HEPATITIS C VIRUS, poster presentation at the 1st Annual ICGNB 2017, NSU, Dhaka.
15) Abu Sayeed Chowdhury, G. M. Sayedur Rahman, Nahid Hasan, Khondker Ayesha Akter, In Silico Approach For Pharmacophore Based Inhibitors Design Targeting FAM98A, FAM98B, FAM98C, poster presentation at the 1st Annual ICGNB 2017, NSU, Dhaka
16) Tasmia Momin, G. M. Sayedur Rahman, Hasan Mahmud Reza, 3D structure determination of the Non-structural proteins and endonuclease enzyme of Human Papilloma Virus-16 as the receptor for the development of new subtype specific Anti-papilloma drugs, poster presentation at the 1st Annual ICGNB 2017, NSU, Dhaka (Awarded: Best poster award, 2nd prize)
17) Momin Ul Haque, A. S. M. Zihad Hossain, G. M. Sayedur Rahman, Hasan Mahmud Reza , 3D structure determination of the Non-structural proteins of Zika Virus (Strain MR 766) as the receptor for the development of new Anti-Zika drugs, poster presentation at the 1st Annual ICGNB 2017, NSU, Dhaka
18) Rahman G. M., Sanker S., Lewin N., Prasad B.V.V., Blumberg P. M., Das J., Comparison of the activator binding residues of PKCθ and PKCδ, podium presentation at the 39th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, Monroe, LA, USA (May 2012).
19) Rahman G. M., Sanker S., Lewin N., Prasad B.V.V., Blumberg P. M., Das J., Identification of the activator binding residues in protein kinase C theta (PKCθ) C1B domain, poster presented at the Experimental Biology Meeting 2012, San Diego, CA, USA (April 2012).
20) Rahman G. M., Das J., Identification of activator binding residues in PKCθ C1B subdomain: The effect of mutation in activator binding, podium presentation at the 38th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, Houston, TX, USA (May 2011).
21) Rahman G. M., Das J., Identification of activator binding residues in C1B subdomain of Protein Kinase C theta (PKCθ), poster presented at the 37th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, Ole Miss, MS, USA (May 2010).
22) Rahman G. M., Das J., Virtual molecular docking study of DAG and Phorbol ester-like compounds to explore the differential binding affinity of C1A and C1B subdomains of novel PKCs, poster presented at the 36th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, Memphis, TN, USA (May 2009).
23) Guillory A. Pany S., Rahman G. M., Das J., Munc 13-1 C1 domain binds alcohol specifically, poster presented at the 36th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, Memphis, TN, USA (May 2009).
24) Pany S., Rahman G. M., Guillory A., Das J., Protein Kinase C epsilon has an alcohol binding site in its regulatory domain, poster presented at the 35th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, Little Rock, AR, USA (May 2008).
ASSITANTSHIPS/ SCHOLARSHIPS/ FELLOWSHIPS/AWARD
1) Travel award from ASBMB for attending Experimental Biology-2012 conference at San Diego, USA
2) Graduate Teaching Assistantship (GTA), University of Houston, College of Pharmacy (2007-2012) for PhD
3) Graduate Assistant Teaching Fellowship (GATF), University of Houston (2007-2012) for Ph. D
4) Bangladesh National Science & Technology Fellowship 1999-2000 (NST-Fellowship) for M. Phil.
5) Scholarship, University of Dhaka (1997-1998) for M. Phil.
6) Bangladesh National Science & Technology Fellowship 1997-1998 (NST-Fellowship) for M. Pharm.
7) Scholarship, University of Dhaka (1993) for B. Pharm. (Hons.).
8) Bangladesh National Cadet Corps Scholarship 1990- 1991 (BNCC).
9) Fazli Hossain Memorial Scholarship, Department of Pharmacy, University of Dhaka (1990- 1991) for achievement in B. Pharm. 1st year final exam.
ACADEMIC QUALIFICATION & CREDENTIALS:
1) Postdoctoral training: Postdoctoral fellowship (2012-2014), Cancer Biology, MD Anderson Cancer, University of Texas, Houston, Texas, USA
2) Doctor of Philosophy (Ph. D.): An earned Ph. D. in Pharmaceutics (2007-2012) from University of Houston College of Pharmacy (UHCOP),Houston, Texas, USA
3) Master of Philosophy (M. Phil.), P-1: 1996-1998, Department of Pharmacy, Faculty of Pharmacy, University of Dhaka, Dhaka
4) Master of Pharmacy (M. Pharm.): 1993-1994, First class, Department of Pharmacy, Faculty of Pharmacy, University of Dhaka, Dhaka
5) Bachelor of Pharmacy (B. Pharm.): 1990-1993, First class, Department of Pharmacy, Faculty of Pharmacy, University of Dhaka, Dhaka
6) Higher Secondary Certificate (HSC): 1990, First Division, Dhaka Board, University Laboratory School & College, Dhaka
7) Secondary School Certificate (SSC): 1988, First Division, Dhaka Board, University Laboratory School & College, Dhaka
ACADEMIC EXPERIENCE:
1) Currently serving as a Full-time Professor (April 01, 2022-Present) in Department of Pharmaceutical Sciences, SHLS, North South University, Dhaka, Bangladesh.
2) Served as the two times Department Chair (February 01, 2019-January 09, 2023) in Department of Pharmaceutical Sciences, SHLS, North South University, Dhaka, Bangladesh.
3) Served as an Associate Professor (March 01, 2017-March 31, 2022) in Department of Pharmaceutical Sciences, SHLS, North South University, Dhaka, Bangladesh.
4) Served as an Assistant Professor (September 29, 2014-February 28, 2017) in Department of Pharmaceutical Sciences, SHLS, North South University, Dhaka, Bangladesh.
5) Post-Doctoral Research Fellow, Cancer Medicine, University of Texas MD Anderson Cancer Center (September 2012-September 2014)
6) During my graduate study in University of Houston College of Pharmacy, I was assigned as Teaching Assistant for pharmaceutics, biopharmaceutics, advanced pharmacokinetics, advanced pharmaceutics and pharmacy compounding skill lab for the Pharm. D students (January 2007-August 2012). The job included mentoring the Pharm. D students, conducting the exams and grading.
7) Assistant Professor, Department of Pharmacy, Northern University Bangladesh, Dhaka (01st July 2006-31st December 2006). I taught physical pharmacy, pharmaceutics, and pharmacokinetics both in under graduate and graduate Pharmacy students.
8) Part Time faculty (Assistant Professor), Department of Pharmacy, Northern University Bangladesh, Dhaka (01st October 2003-30th June 2006). I taught physical pharmacy, pharmaceutics, and pharmacokinetics course for both under graduate and graduate Pharmacy students.
9) Part time faculty for Advanced Chemistry & Biology, O-Level and A-Level, Oxford International School, Dhaka, Bangladesh (10th January 2001-30th June 2005).
10) Lecturer, Pharmacy Discipline, Khulna University, Bangladesh (18th October 1998-31st December 2000). I taught physical pharmacy, pharmaceutics, pharmacokinetics, and medicinal chemistry, biomolecular pharmacy and biochemistry courses for both under graduate and graduate Pharmacy students.
CORPORATE EXPERIENCE:
1) Quality Control Officer, SK+F Pharmaceuticals Bangladesh Ltd., Dhaka (01st November 1997-14th October 1998). (mentioned before in professional strength)
2) Trainee Pharmacist: Completed one-month hands on in-plant training (part of B. Pharm. courses) in BEXIMCO Pharmaceuticals Ltd. Bangladesh, one of country’s largest Pharmaceutical Industry to strengthen the pharmaceutical knowledge base and the understanding of pharmacological aspects of drugs. Training included on Solid Pharmaceuticals, Liquids, Infusions, Pharmaceutical raw materials, Antibiotics, Quality Control and Quality Assurance, Pharmaceutical Engineering and Marketing (03rd August 1995-04th September 1995).
TEACHING AREAS AND FIELDS OF SPECIALIZATION:
Undergraduate (BPharm):
Currently teaching:
1) Pharmaceutical Dispensing
2) Biopharmaceutics & Pharmacokinetics
3) Drug Information
Previously taught:
1) Introduction to Pharmacy
2) Pharmacognosy
3) Pharmaceutical Calculations
4) Physical Pharmacy
5) Microbiology
6) Medicinal Chemistry
7) Pharmaceutical Analysis
8) Organic Pharmacy
9) Inorganic Pharmacy
Masters (MPharm):
Currently teaching:
1) Advanced Pharmaceutical Statistics
2) Advanced Biopharmaceutics & Pharmacokinetics
Previously taught:
1) Toxicology & Safety Pharmacology
2) Drug Design
MEMBERSHIPS IN PROFESSIONAL ORGANIZATIONS:
1. American Association of Cancer Research (AACR)
2. The Smithsonian Institution
3. American Association of Pharmaceutical Scientists (AAPS)
4. American Society of Biochemistry and Molecular Biology (ASBMB)
5. National Geographic Society (NGS)
6. Bangladeshi American Pharmacists Association (BAPA)
7. Asiatic Society of Bangladesh (ASB)
8. Registered Pharmacist (Grade-A, #1633), Bangladesh Pharmacy Council (PCB), Bangladesh
9. Bangladesh Pharmaceutical Society (BPS)
10. Pharmacy Graduates Association of Bangladesh (PGA)
RESEARCH INTEREST:
My PhD training was on the area of 3D protein structure determination using X-ray crystallography. The research title defended was “Identification of the Activator Binding Residues in the Second Cysteine-Rich Regulatory Domain of Protein Kinase C Theta”. The kind of research facility I used during my PhD was expensive and cutting edge, which an institution in a developing country can barely afford it. Now with the advancement of computational power and speed and AI, the alternate process of computational protein structure design made it within reach to do research with limited computational facility that we can afford.
At this stage of my teaching career in NSU, I am trying to make a balance in the time dedicated for active class room teaching in both undergrad and graduate level and my research focus. I am currently engaged in Computational drug design and in-silico protein structure modelling.
To design the new drug molecule, I also apply different tools and software. Amongst the tools and software (freeware), I mostly use those are free to use, as a part of the research collaboration agreement between the educational institutions and the tools developing organizations. In course of time, we also collected some of the software form different sources.
The kind of computational works that we do as part of the in-silico drug design are.
1) Homology protein modeling
2) ab-initio protein modeling
3) Protein fragments joining
4) Protein structure energy minimization for stability
5) Protein surface topology scanning for substrate binding pocket identification
6) Substrate design and energy minimization
7) Molecular modeling
8) Molecular dynamics
9) Database search for both the target proteins and substrate
10) Pharmacophore based database search for the similar molecules
11) ADME prediction for the selected drugable molecules
12) Toxicity prediction of the selected molecules
In addition to my area of focus of computational drug design, I also collaborate with other faculties in the department those who are engaged in phytochemical medicine research, new drug pharmacology and survey-based research on certain population segments for certain Public Health interests.