Center of Excellence in Higher Education
The First Private University in Bangladesh

Dr. Ariful Islam

Full Time Faculty
Assistant Professor

PhD in Medical Sciences, Hamamatsu University School of Medicine, Shizuoka, Japan
MSc in Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi, Bangladesh

Phone: +880-2-55668200, Ext. 6846
Email: islam.ariful02@northsouth.edu 
Office: SAC832A

Curriculum Vitae 

 

Dr. Ariful Islam is currently working as an Assistant Professor at the Department of Biochemistry & Microbiology of North South University, Dhaka, Bangladesh (since January 2024). Previously, he worked as a Postdoctoral Researcher at Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan (October 2021 to January 2024). During that time, he worked on drug pharmacokinetics, metabolomics, lipidomics and proteomics of human and animal samples applying mass spectrometry imaging (MSI) and liquid chromatography-mass spectrometry (LC-MS & LC-MS/MS). He has also worked as a Researcher at Preppers Ltd. Co. (a bio-venture company, https://www.preppers.co.jp/) from January 2020 to March 2023, and as a Research Associate from April 2023 to January 2024. 

He obtained PhD degree in Medical Sciences from Hamamatsu University School of Medicine, Hamamtsu, Japan, under the supervision of Professor Mitsutoshi Setou (October 2017 to September 2021). During his PhD, he focused on behavioral, metabolomic, and lipidomic alternations in neurodegenerative diseases, and in the discovery of antiaging molecules from natural sources.

He has completed his bachelor of science (BSc) and mater of scinece (MSc) degrees in Biochemistry and Molecular Biology from the University of Rajshahi, Rajshahi, Bangladesh. During his MSc thesis, he worked on the antidiabetic and anti-cancer properties of natural products.

He has published more than 30 research and review articles in reputed journals during his MSc, PhD, and Postdoctoral research works.

 

Google Scholar: https://scholar.google.com/citations?user=aeTfCmAAAAAJ&hl=en

LinkedIn: https://www.linkedin.com/in/ariful-islam-28a7701a7/ 

Orchid: https://orcid.org/my-orcid?orcid=0000-0001-7497-3540 

Publications

  1. Rahman MF, Islam A, Islam MM, Mamun MA, et al. Mass Spectrometry Imaging Combined with Sparse Autoencoder Method Reveals Altered Phosphorylcholine Distribution in Imipramine Treated Wild-Type Mice Brains. International Journal of Molecular Sciences, 2024. DOI: 10.3390/ijms25147969.
  2. Rahman MM, Islam A, Mamun MA, Afroz MS, et al. Low-temperature plasma pre-treatment enhanced cholesterol detection in brain by desorption electrospray ionization-mass spectrometry imaging. J. Am. Soc. Mass Spectrom., 2024. DOI: 10.1021/jasms.4c00045.
  3. Islam MM, Rahman MF, Islam A, Afroz MS, et al. Elucidating Gender-Specific Distribution of Imipramine, Chloroquine, and their Metabolites in the Mice Kidney Tissues through AP-MALDI-MSI. International Journal of Molecular Sciences, 2024. DOI: 10.3390/ijms25094840.
  4. Tamannaa Z, Sakamoto T, Mamun Md. A, Oyama S, Waliullah ASM, Islam A, et al. DESI-IMS coupled with triple quadrupole mass spectrometry demonstrated the capability of NMN imaging in Shelfordella lateralis tissue. Medical Mass Spectrometry, 2024. DOI: 10.24508/mms.2024.06.001.
  5. Li W, Zhang C, Aramaki S, Xu L, ….., Islam A, et al. Lipid Polyunsaturated Fatty Acid Chains in Mouse Kidneys Were Increased within 5 min of a Single High Dose Whole Body Irradiation. International Journal of Molecular Sciences, 2023. DOI: 10.3390/ijms241512439.
  6. Tasaki E, Mitaka MY, Takahashi Y, Waliullah ASM, …..Islam A, et al. The royal food of termites shows king and queen specificity. PNAS Nexus, 2023. DOI: 10.1093/pnasnexus/pgad222.
  7. Mamun MA, Rahman MR, Sakamoto T, Islam A, et al. Detection of Distinct Distributions of Acetaminophen and Acetaminophen-Cysteine in Kidneys up to 10 µm Resolution and Identification of a Novel Acetaminophen Metabolite Using AP-MALDI Imaging Mass Microscope. Am. Soc. Mass Spectrom., 2023. DOI: 10.1021/jasms.3c00149.
  8. Aramaki S, Tsuge S, Islam A, Eto F, et al. Lipidomics-based tissue heterogeneity in specimens of luminal breast cancer revealed by clustering analysis of mass spectrometry imaging: A preliminary study. PloS one, 2023. DOI: 10.1371/journal.pone.0283155.
  9. Ping Y, Ohata K, Kikushima K, Sakamoto T, Islam A, et al. Tubulin Polyglutamylation by TTLL1 and TTLL7 Regulate Glutamate Concentration in the Mice Brain. Biomolecules, 2023. DOI: 10.3390/biom13050784.
  10. Xu L, Kikushima K, Sato S, Islam A, Sato T, et al. Spatial distribution of the Shannon entropy for mass spectrometry imaging. PloS one, 2023. DOI: 10.1371/journal.pone.0283966.
  11. Zhai Q, Islam A, Chen B, Zhang H, Chi DH, et al. Endocannabinoid 2-Arachidonoylglycerol Levels in the Anterior Cingulate Cortex, Caudate Putamen, Nucleus Accumbens, and Piriform Cortex Were Upregulated by Chronic Restraint Stress. Cells, 2023. DOI: 3390/cells12030393.
  12. Zhang C, Kikushima K, Endo M, Kahyo T, ... Islam A, et al. Imaging and manipulation of plasma membrane fatty acids clusters using TOF-SIMS combined optogenetics. Cells, DOI: 10.3390/cells12010010.
  13. Kurosu K, Islam A, Sato T, Kahyo T, Banno T, et al. Expression and kinetics of endogenous cannabinoids in brain and spinal cord of a spare nerve injury (SNI) model of neuropathic pain. Cells, 2022. DOI: 10.3390/cells11244130.
  14. Islam A, Sakamoto T, Zhai Q, Rahman MR, Mamun MA, et al. Application of AP-MALDI Imaging Mass Microscope for the Rapid Mapping of Imipramine, Chloroquine, and Their Metabolites in the Kidney and Brain of Wild-Type Mice. Pharmaceuticals, 2022. DOI: 10.3390/ph15111314.
  15. Yan J, Sakamoto T, Islam A, Ping Y, Oyama S, et al. Cinnamomum verum J. Presl Bark Contains High Contents of Nicotinamide Mononucleotide. Molecules, 2022. DOI: 10.3390/molecules27207054.
  16. Yamada H, Xu L, Eto F, Takeichi R, Islam A, et al. Changes of Mass Spectra Patterns on a Brain Tissue Section Revealed by Deep Learning with Imaging Mass Spectrometry Data. J. Am. Soc. Mass Spectrom., 2022. DOI: 10.1021/jasms.2c00080.
  17. Mamun MA, Nabi MM, Sato T, Aramaki S,….. Islam A, et al. Coenzyme Q10 in the eye isomerizes by sunlight irradiation. Sci. Rep., 2022. DOI: 10.1038/s41598-022-16343-8.
  18. Nabi MM, Sakamoto T, Mamun MA, Islam A, Waliullah ASM, et al. A convenient online desalination tube coupled with mass spectrometry for the direct detection of iodinated contrast media in untreated human spent hemodialysates. PloS one, 2022. DOI: 10.1371/journal.pone.0268751.
  19. Akita K, Kikushima K, Ikoma T, Islam A, Sato T, et al. The association between the clinical severity of heart failure and docosahexaenoic acid accumulation in hypertrophic cardiomyopathy. BMC Research Notes, 2022. DOI: 10.1186/s13104-022-06023-1.
  20. Islam A, Takeyama E, Nabi MM, Zhai Q, Fukushima M, et al. Stress upregulates 2-arachidonoylglycerol levels in the hypothalamus, midbrain, and hindbrain, and it is sustained by green nut oil supplementation in SAMP8 mice revealed by DESI-MSI. BBRC, 2022. DOI: 10.1016/j.bbrc.2022.04.004.
  21. Chi DH, Kahyo T, Islam A, Hasan MM, Waliullah ASM, et al. NAD+ Levels Are Augmented in Aortic Tissue of ApoE−/− Mice by Dietary Omega-3 Fatty Acids. ATVB, 2022. DOI: 10.1161/ATVBAHA.121.317166
  22. Takeda Rϯ, Islam Aϯ (ϯequal contribution), Sato T, Kurita H, Kahyo T, et al. The stability of the metabolic turnover of arachidonic acid in human unruptured intracranial aneurysmal walls is sustained. Clinical Neurology and Neurosurgery, 2021. DOI: 10.1016/j.clineuro.2021.106881.
  23. Mamun MA, Islam A, Hasan MM, Waliullah ASM, Tamannaa Z, et al. The human vermilion surface contains a rich amount of cholesterol sulfate than the skin. Journal of Dermatological Science, 2021. DOI: 10.1016/j.jdermsci.2021.07.008.
  24. Hasan MM, Mimi MA, Mamun MA, Islam A, Waliullah ASM, et al. Mass spectrometry imaging of glycome in the brain. Frontiers in Neuroanatomy, 2021. DOI: 10.3389/fnana.2021.711955.
  25. Nabi MM, Mamun MA, Islam A, Hasan MM, Waliullah ASM, et al. Mass spectrometry in the lipid study of cancer. Expert review of proteomics, 2021. DOI: 10.1080/14789450.2021.1912602.
  26. Hasan MM, Eto F, Mamun MA, Sato S, Islam A, et al. DIUTHAME offers higher reproducibility than DHB, a widely used matrix, in FT-ICR mass spectrometric analysis. Rapid communications in mass spectrometry, 2021. DOI: 10.1002/rcm.9076.
  27. Bari MW, Islam A, Islam MM, Sultana MJ, Afroz R, et al. Determination of in vitro antioxidant activity and in vivo antineoplastic effects against Ehrlich ascites carcinoma of methanolic extract of Sphagneticola calendulacea (L.) Pruski. Heliyon, 2021. DOI: 10.1016/j.heliyon.2021.e07228.
  28. Mamun MA, Islam A, Eto F, Sato T, Kahyo T, et al. Mass spectrometry-based phospholipid imaging: methods and findings. Expert review of proteomics, 2020. DOI: 10.1080/14789450.2020.1880897.
  29. Islam A, Takeyama E, Mamun MA, Sato T, Horikawa M, et al. Green nut oil or DHA supplementation restored decreased distribution levels of DHA containing phosphatidylcholines in the brain of a mouse model of dementia. Metabolites, 2020. DOI: 10.3390/metabo10040153.
  30. Mamun MA, Sato S, Naru E, Sakata O, ……., Islam A, et al. Higher accumulation of docosahexaenoic acid in the vermilion of the human lip than in the skin. International Journal of Molecular Sciences, 2020. DOI: 10.3390/ijms21082807.
  31. Bari MW, Islam MM, Khatun M, Sultana MJ, Ahmed R, Islam A, et al. Antidiabetic effect of Wedelia chinensis leaf extract in alloxan-induced Swiss albino diabetic mice. Clinical Phytoscience, 2020. DOI: 10.1186/s40816-020-00197-6.
  32. Takeyama Eϯ, Islam Aϯ (ϯequal contribution), Watanabe N, Tsubaki H, Fukushima M, et al. Dietary intake of green nut oil or DHA ameliorates DHA distribution in the brain of a mouse model of dementia accompanied by memory recovery. Nutrients, 2019. DOI: 10.3390/nu11102371.
  33. Mamun MA, Gonzalez TV, Islam A, Sato T, Sato S, et al. Analysis of potential anti-aging beverage Pru, a traditional Cuban refreshment, by desorption electrospray ionization-mass spectrometry and FTICR tandem mass spectrometry. Journal of Food and Drug Analysis, 2019. DOI: 10.1016/j.jfda.2019.05.004.

 

Book/Chapter

1. Oyama S, Zhang C, Islam A, Aramaki S, Sato T, et al. 治療標的がみえてきた脂質疾患学 (Lipid disease science has revealed therapeutic targets), 第 4.3章 : ヒト検体の質量分析イメージング (Chapter 4.3: Mass spectrometry imaging of human specimens). 実験医学増刊 (Experimental Medicine Special Issue) Vol.41 No.17. Page 242-249. https://www.yodosha.co.jp/jikkenigaku/book/9784758104142/index.html.

 

Conference Participation

  1. Islam A, Zhai Q, Rahman MM, Takahashi Y, Sakamoto T, et al. Rapid Mapping of Imipramine, Chloroquine and Their Metabolites in Mice by AP-MALDI Mass Spectrometry Imaging Combined with Product-Ion Analysis. 71st MSSJ Conference on Mass Spectrometry. Poster (May 2023, Osaka, Japan).
  2. Islam A, Zhai Q, Rahman MM, Takahashi Y, Sakamoto T, et al. Rapid localization of Imipramine, Chloroquine and Their Metabolites in Wild-Type Mice by Atmospheric Pressure Matrix-assisted Laser Desorption Ionization Mass Spectrometry Imaging Combined with Product-Ion Analysis. 6th International Symposium of the Kyoto Biomolecular Mass Spectrometry Society. Poster (March 2023, Tohoku University, Sendai, Japan).
  3. Islam A, Zhai Q, Rahman MM, Takahashi Y, Sakamoto T, et al. Rapid localization of Small Drugs by Atmospheric Pressure Matrix‐assisted Laser Desorption Ionization Mass Spectrometry Imaging Combined with Product-Ion Analysis. 128th Annual Meeting of The Japanese Association of Anatomists. Poster (January 2023, Kyoto, Japan).
  4. Islam A, Takahashi Y, Sakamoto T, Aramaki S, Mamun MA, et al. Pharmacokinetic Analysis of Small Drugs by Mass Spectrometry Imaging Combined with Product-Ion Analysis. 70th MSSJ Conference on Mass Spectrometry. Poster (June 2022, Fukuoka, Japan).
  5. Islam A, Takahashi Y, Aramaki S, Sakamoto T, Mamun MA, et al. Rapid pharmacokinetic analysis of small drugs by mass spectrometry imaging combined with product ion analysis. 70th ASMS Conference on Mass Spectrometry and Allied Topics. Poster (June 2022, Minneapolis, Minnesota, USA).
  6. Islam A, Zhai Q, Nabi MM, Mamum MA. Kikushima K, et al. Effects of stress on brain 2-arachidonoylglycerol and prostaglandins in wild-type mice. 63rd Annual Meeting of the Japanese Biochemical Society. Oral (May 2021, Online).
  7. Islam A, Takeda R, Sato T, Kurita H, Waliullah ASM, et al. DESI-IMS revealed the association of linoleic acid, oleic acid and arachidonic acid in the rupture of cerebral aneurysm. 67th ASMS Conference on Mass Spectrometry and Allied Topics. Poster (June 2019, Georgia, Atlanta, USA).
  8. Islam A, Takeyama E, Watanabe N, Tsubaki H, Fukushima M, et al. Dietary intake of green nut oil and DHA ameliorate memory efficiency and DHA levels in cerebellum, hippocampus and olfactory bulb of Alzheimer disease model mice (SAMP8). 60th International Conference on the Bioscience of Lipids. Poster (June 2019, Tokyo, Japan).
  9. Islam A, Takeda R, Sato T, Kurita H, Horikawa M, et al. DESI-IMS revealed the association of arachidonic acid in the rupture of intracranial aneurysmal walls in humans. The 44th Annual Meeting of the Japanese Society for Biomedical Mass Spectrometry. Poster (December 2019, Nagoya, Japan).
  10. Islam A, Takeda R, Sato T, Kurita H, Horikawa M, et al. Arachidonic acid is increased approximately 300 times in the walls of ruptured intracranial aneurysms compared to the walls of unruptured intracranial aneurysms in humans. 4th LQ meeting. Poster (January 2020, Ito, Shizuoka, Japan).
  1. Hamamatsu University School of Medicine International Students Exchange Scholarship (2017).
  2. National Science and Technology (NST) Fellowship, Bangladesh (2016).

PhD in Medical Sciences, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan (September 2021)

MSc in Biochemistry & Molecular Biology, University of Rajshahi, Bangladesh (2017)

BSc in Biochemistry & Molecular Biology, University of Rajshahi, Bangladesh (2015)

  1. Assistant Professor at the Department of Biochemistry & Microbiology, North South University, Dhaka, Bangladesh. Duration: 21st January 2024 to present.
  1. Postdoctoral Researcher at the Department of Cellular and Molecular Anatomy, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan. Duration: 1st October 2021 to 16th January 2024.
  1. Researcher at Preppers Co., Ltd., Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan (https://www.preppers.co.jp/). Duration: 1st January 2020 to 31st March 2023.
  2. Research Associate at Preppers Co., Ltd., Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan (https://www.preppers.co.jp/). Duration: 1st April 2023 to 16th January 2024.

BIO201- Introduction to Biochemistry & Biotechnology

BBT221- Human Physiology 

BIO103- Biology I

BIO201L- Introduction to Biochemistry & Biotechnology Lab

BIO103L- Biology I Lab

CHE101L- General Chemistry Lab

  1. The American Society for Mass Spectrometry (ASMS). From January 2019 to present.
  2. Japanese Association of Anatomists (JAA). From April 2022 to March 2024.
  3. Kyoto Biomolecular Mass Spectrometry Society (KBMSS). From April 2022 to present.
  4. Japanese Society for Biomedical Mass Spectrometry (JSBMS). From April 2019 to March 2023.

1. Proteomics

2. Metabolomics

3. Cancer Biology

4. Natural Products