Center of Excellence in Higher Education
The First Private University in Bangladesh

Dr. Asim Kumar Bepari

Full Time Faculty
Professor 

PhD (Neuroscience), Kumamoto University, Japan
MPharm, Jahangirnagar University, Bangladesh

Email: asim.bepari@northsouth.edu
Curriculum Vitae
 Scopus Author ID: 54398230600                      ResearcherID: D-4001-2013
 ORCID icon http://orcid.org/0000-0001-5656-1833
 
 
 

Dr. Asim Kumar Bepari is passionate for teaching and research. His works are aiming in understanding pathophysiology of human diseases, and in the long run, finding better therapeutic interventions to improve quality of life. He obtained his Bachelor of Pharmacy Honors (BPharm Honors) and Master of Pharmacy (MPharm) from Jahangirnagar University, Bangladesh. He is a registered pharmacist (A-Grade) with the Pharmacy Council of Bangladesh. During undergraduate and graduate studies in pharmaceutical sciences Dr. Bepari worked on market status and quality of antibacterial agents. In 2002, Dr. Bepari started his career in The Acme Laboratories Ltd. which is a leading pharmaceutical company in Bangladesh. In Acme, he developed strong leadership, communication and administrative skills while working as an executive and later as the coordinator of the International Marketing section.

Dr. Bepari started his journey as a teacher in the Department of Pharmacy at Stamford University Bangladesh (SUB) from 2004 and then switched to the North South University (NSU), Bangladesh in 2007. Since NSU Pharmacy was at a nascent stage at that time, Dr. Bepari had the opportunity to experience and to be actively involved in the rapid progress of the department. He was in Kumamoto University, Kumamoto, Japan for his doctoral study (2009-2013) in life sciences. For mapping brain activity he utilized different sophisticated techniques of molecular and cellular neuroscience using in vivo (mouse, chick) and cell culture models. His research findings were published in high impact peer reviewed international journals. Dr. Bepari worked as a guest researcher (Jan-Dec, 2012) and as a postdoctoral researcher (Apr-Jun, 2013) in the laboratory of Professor Dr. Hirohide Takebayashi in the Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.

At NSU Pharmacy, Dr. Bepari has been teaching several courses including human phyiology, pharmaceutical analysis and pharmaceutical chemistry. He is also an external examiner of Jahangirnagar University from 2005. In collaboration with Professor Hirohide Takabayashi’s research group in Japna and with fellow researchers at NSU, Dr. Bepari is working on several projects including brain lateralization and molecular mechanisms regulating nervous system development. Dr. Bepari completed his posdoctoral training in the University of Texas Southwestern Medical Centre, Dallas, Texas, USA.

  1. Namme, J. N.; Reza, H. M.; Bepari, A. K. Unraveling the Impact of ZG16B Missense Mutations: Computational Prediction of Structural and Functional Consequences. In Silico Pharmacol. 2025, 13 (2), 79. https://doi.org/10.1007/s40203-025-00366-w.
  2. Hossain, N.; Shabnam, S.; Emran, T.; Zahid, Z. I.; Alam, S.; Bepari, A. K.; Sayedur Rahman, G. M.; Reza, H. M. Coenzyme Q10 Alleviates Oxidative Stress, Inflammation and Fibrosis via Activation of TGFβ1/TNF-α in FCA-Salt Hypertensive Rats. Biochem. Biophys. 2025, 769, 110444. https://doi.org/10.1016/j.abb.2025.110444.
  3. Biswas, A. M.; Emran, T.; Khan, S. I.; Shabnam, S.; Jain, P.; Bepari, A. K.; Shill, M. C.; Hossain, M. M.; Reza, H. M. Transforming Growth Factor-β-Mediated Attenuation of Cardio-Renal Oxidative Stress, Inflammation and Fibrosis by L-Arginine in Fludrocortisone Acetate Induced-Hypertensive Rats. J. Pharmacol. 2025, 996, 177559. https://doi.org/10.1016/j.ejphar.2025.177559.
  4. Tondar, A.; Irfan, M.; Sánchez-Herrero, S.; Athar, H.; Haqqi, A.; Bepari, A. K.; Liñán, L. C.; Marin, D. H. In-Silico Structural and Functional Analysis of Nonsynonymous Single Nucleotide Polymorphisms in Human FOLH1 Gene. In Silico Pharmacol. 2025.
  5. Shama, A. T.; Shova, L. M.; Bristy, A. T.; Emran, T.; Shabnam, S.; Shill, M. C.; Bepari, A. K.; Reza, H. M. Anti-Obesity Effects and Underlying Molecular Mechanisms of the Ethanolic Extract of Figs from Ficus Hispida Using High Fat-Fed Wister Rats. Heliyon 2024, 10 (15). https://doi.org/10.1016/j.heliyon.2024.e35392.
  6. Tondar, A.; Sánchez-Herrero, S.; Bepari, A. K.; Bahmani, A.; Calvet Liñán, L.; Hervás-Marín, D. Virtual Screening of Small Molecules Targeting BCL2 with Machine Learning, Molecular Docking, and MD Simulation. Biomolecules 2024, 14 (5), 544. https://doi.org/10.3390/biom14050544.
  7. Bepari, A. K.; Shatabda, S.; Reza, H. M. Virtual Screening of Flavonoids as Potential RIPK1 Inhibitors for Neurodegeneration Therapy. PeerJ 2024, 12.
  8. Bepari, A. K.; Rabbi, G.; Shaon, H. R.; Khan, S. I.; Zahid, Z. I.; Dalal, K.; Reza, H. M. Factors Driving Antimicrobial Resistance in Rural Bangladesh: A Cross-Sectional Study on Antibiotic Use-Related Knowledge, Attitude, and Practice Among Unqualified Village Medical Practitioners and Pharmacy Shopkeepers. Ther. 2023, 40 (8), 3478–3494. https://doi.org/10.1007/s12325-023-02547-5.
  9. Johra, F. T.; Hossain, S.; Jain, P.; Bristy, A. T.; Emran, T.; Ahmed, R.; Sharker, S. M.; Bepari, A. K.; Reza, H. M. Amelioration of CCl4-Induced Oxidative Stress and Hepatotoxicity by Ganoderma Lucidum in Long Evans Rats. Rep. 2023, 13 (1), 9909. https://doi.org/10.1038/s41598-023-35228-y.
  10. Namme, J. N.; Reza, H. M.; Bepari, A. K. Computational Analysis and Molecular Dynamics Simulation of High-Risk Single Nucleotide Polymorphisms of the ADAM10 J. Biomol. Struct. Dyn. 2023, 1–13. https://doi.org/10.1080/07391102.2023.2192890.
  11. Hossain, M.; Suchi, T. T.; Samiha, F.; Islam, M. M. M.; Tully, F. A.; Hasan, J.; Rahman, M. A.; Shill, M. C.; Bepari, A. K.; Rahman, G. M. S.; Reza, H. M. Coenzyme Q10 Ameliorates Carbofuran Induced Hepatotoxicity and Nephrotoxicity in Wister Rats. Heliyon 2023, 9 (2), e13727. https://doi.org/10.1016/j.heliyon.2023.e13727.
  12. Shill, M. C.; Biswas, B.; Kamal, S.; Islam, M.; Rima, S. S.; Ferdausi, F. A.; Chowdhury, Q.; Reza, H. M.; Bepari, A. K. Screening of Plasma IL-6 and IL-17 in Bangladeshi Lung Cancer Patients. Heliyon 2023, 9 (10).
  13. Bepari, A. K.; Takebayashi, H.; Namme, J. N.; Rahman, G. M. S.; Reza, H. M. A Computational Study to Target Necroptosis via RIPK1 Inhibition. Biomol. Struct. Dyn. 2022, 1–16. https://doi.org/10.1080/07391102.2022.2108900.
  14. Rahman, M. A.; Shuvo, A. A.; Bepari, A. K.; Apu, M. H.; Shill, M. C.; Hossain, M.; Uddin, M.; Islam, M. R.; Bakshi, M. K.; Hasan, J.; Rahman, A.; Rahman, G. M. S.; Reza, H. M. Curcumin Improves D-Galactose and Normal-Aging Associated Memory Impairment in Mice: In Vivo and in Silico-Based Studies. PLOS ONE 2022, 17 (6), e0270123. https://doi.org/10.1371/journal.pone.0270123.
  15. Bizen, N.; Bepari, A. K.; Zhou, L.; Abe, M.; Sakimura, K.; Ono, K.; Takebayashi, H. Ddx20, an Olig2 Binding Factor, Governs the Survival of Neural and Oligodendrocyte Progenitor Cells via Proper Mdm2 Splicing and P53 Suppression. Cell Death Differ. 2022, 1–14. https://doi.org/10.1038/s41418-021-00915-8.
  16. Bepari, A. K.; Reza, H. M. Identification of a Novel Inhibitor of SARS-CoV-2 3CL-PRO through Virtual Screening and Molecular Dynamics Simulation. PeerJ 2021, 9, e11261. https://doi.org/10.7717/peerj.11261.
  17. Bari, R.; Bepari, A. K.; Reza, H. M. COVID-19: Lessons from Norway Tragedy Must Be Considered in Vaccine Rollout Planning in Least Developed/Developing Countries. Open Med. 2021, 16 (1), 1168–1169.
  18. Namme, J. N.; Bepari, A. K.; Takebayashi, H. Cofilin Signaling in the CNS Physiology and Neurodegeneration. J. Mol. Sci. 2021, 22 (19), 10727. https://doi.org/10.3390/ijms221910727.
  19. Shill, M. C.; Bepari, A. K.; Khan, M.; Tasneem, Z.; Ahmed, T.; Hasan, M. A.; Alam, M. J.; Hossain, M.; Rahman, M. A.; Sharker, S. M.; Shahriar, M.; Rahman, G. M. S.; Reza, H. M. Therapeutic Potentials of Colocasia Affinis Leaf Extract for the Alleviation of Streptozotocin-Induced Diabetes and Diabetic Complications: In Vivo and in Silico-Based Studies. Inflamm. Res. 2021, 14, 443–459. https://doi.org/10.2147/JIR.S297348.
  20. Jain, P.; Bepari, A. K.; Sen, P. K.; Rafe, T.; Imtiaz, R.; Hossain, M.; Reza, H. M. High Prevalence of Multiple Antibiotic Resistance in Clinical E. Coli Isolates from Bangladesh and Prediction of Molecular Resistance Determinants Using WGS of an XDR Isolate. Rep. 2021, 11 (1), 1–13.
  21. Emran, T.; Chowdhury, N. I.; Sarker, M.; Bepari, A. K.; Hossain, M.; Rahman, G. M. S.; Reza, H. M. L-Carnitine Protects Cardiac Damage by Reducing Oxidative Stress and Inflammatory Response via Inhibition of Tumor Necrosis Factor-Alpha and Interleukin-1beta against Isoproterenol-Induced Myocardial Infarction. Pharmacother. 2021, 143, 112139. https://doi.org/10.1016/j.biopha.2021.112139.
  22. Bari, R.; Bepari, A. K.; Reza, H. M. Building Confidence in COVID-19 Vaccine Rollout: The Importance of Responsible Presentation and Follow-on Investigation of Adverse Events Following Immunization (AEFI) Reports for Elderly Patients. J. Med. Public Health 2021, 10 (1), 4.
  23. Akash, S. Z.; Lucky, F. Y.; Hossain, M.; Bepari, A. K.; Rahman, G. M.; Reza, H. M.; Sharker, S. M. Remote Temperature-Responsive Parafilm Dermal Patch for On-Demand Topical Drug Delivery. Micromachines 2021, 12 (8), 975.
  24. Reza, H. M.; Saleh, R.; Jain, P.; Rahman, G. M. S.; Bepari, A. K. C-MAF Expression in Adult Human Ocular Surface and Its Implication in Pterygium Pathogenesis. Biochem. Mol. Biol. 2020, 8 (4), 419–428.
  25. Johra, F. T.; Bepari, A. K.; Bristy, A. T.; Reza, H. M. A Mechanistic Review of β-Carotene, Lutein, and Zeaxanthin in Eye Health and Disease. Antioxidants 2020, 9 (11), 1046. https://doi.org/10.3390/antiox9111046.
  26. Toda, H.; Kawasaki, K.; Sato, S.; Horie, M.; Nakahara, K.; Bepari, A. K.; Sawahata, H.; Suzuki, T.; Okado, H.; Takebayashi, H.; others. Locally Induced Neuronal Synchrony Precisely Propagates to Specific Cortical Areas without Rhythm Distortion. Rep. 2018, 8 (1), 1–15.
  27. Talebian, A.; Britton, R.; Ammanuel, S.; Bepari, A.; Sprouse, F.; Birnbaum, S. G.; Szabó, G.; Tamamaki, N.; Gibson, J.; Henkemeyer, M. Autonomous and Non-Autonomous Roles for Ephrin-B in Interneuron Migration. Biol. 2017, 431 (2), 179–193. https://doi.org/10.1016/j.ydbio.2017.09.024.
  28. Pohlkamp, T.; Xiao, L.; Sultana, R.; Bepari, A.; Bock, H. H.; Henkemeyer, M.; Herz, J. Ephrin Bs and Canonical Reelin Signalling. Nature 2016, 539 (7630), E4–E6. https://doi.org/10.1038/nature20129.
  29. Horie, M.; Watanabe, K.; Bepari, A. K.; Nashimoto, J.; Araki, K.; Sano, H.; Chiken, S.; Nambu, A.; Ono, K.; Ikenaka, K.; Kakita, A.; Yamamura, K.; Takebayashi, H. Disruption of Actin-Binding Domain-Containing Dystonin Protein Causes Dystonia Musculorum in Mice. J. Neurosci. 2014, 40 (10), 3458–3471. https://doi.org/10.1111/ejn.12711.
  30. Bepari, A. K.; Watanabe, K.; Yamaguchi, M.; Tamamaki, N.; Takebayashi, H. Visualization of Odor-Induced Neuronal Activity by Immediate Early Gene Expression. BMC Neurosci. 2012, 13 (1), 140. https://doi.org/10.1186/1471-2202-13-140.
  31. Bepari, A. K.; Sano, H.; Tamamaki, N.; Nambu, A.; Tanaka, K. F.; Takebayashi, H. Identification of Optogenetically Activated Striatal Medium Spiny Neurons by Npas4 Expression. PLoS ONE 2012, 7 (12), e52783. https://doi.org/10.1371/journal.pone.0052783.
  32. Watanabe, K.; Takebayashi, H.; Bepari, A. K.; Esumi, S.; Yanagawa, Y.; Tamamaki, N. Dpy19l1, a Multi-Transmembrane Protein, Regulates the Radial Migration of Glutamatergic Neurons in the Developing Cerebral Cortex. Development 2011, 138 (22), 4979–4990. https://doi.org/10.1242/dev.068155.

2025-2025

Bangladesh Medical Research Council (BMRC) Research Grant (BMRC/Revenue/Research Grant/2025/191(1-10))

Grant Amount: USD 4,104 (BDT 500,000)

Role: Principal Investigator

2022-2024

United International University Institute for Advanced Research (UIU-IAR) Research Grant (UIU-IAR-01-2022-SE-15)

Grant Amount: USD 4,204 (BDT 496,158)

Role: Principal Investigator

2022-2023

North South University CTRG Grant 2022

Grant amount: USD 3,822 (BDT 451,000)

Role: Principal Investigator

2019-2020

North South University CTRG Grant (CTRG-19/SHSL/19)

Grant amount: USD 3,397 (BDT 400,900)

Role: Principal Investigator

2018-2019

North South University CTRG Grant (NSU-RP-18-08)

Grant amount: USD 3,390 (BDT 400,000)

Role: Principal Investigator

2015-2017

Postdoctoral Fellowship at UT Southwestern Medical Center, Dallas, Texas, USA

Funded by the Department of Defense (DAMD 11115013) (PI: Prof. Dr. Mark Henkemeyer)

Fellowship amount: USD 92,000

Role: Postdoctoral Researcher

2009-2013

Japanese Government (Monbukagakusho: MEXT) Scholarship

Stipend amount: USD 43,758 (JPY 6,435,000)

Role: Doctoral Researcher

2011

G-COE Research Funding Project for Young Scientists

Kumamoto University, Japan

Grant amount: USD 3,400 (JPY 500,000)

Role: Investigator (Young Scientist)

2011

Fellowship of Global COE, Kumamoto University, Japan

Fellowship amount: USD 2,040 (JPY 300,000)

Role: Global COE Jr. Research Associate

2011

GCOE Travel Award for Young Scientists, Global COE, Kumamoto University, Japan.

2001-2022

Jahangirnagar University Postgraduate Scholarship for excellent academic results in M.Pharm.

1996-2000

Jahangirnagar University Undergraduate Scholarship for excellent academic results in B.Pharm (Honours).

2013

PhD in Life Sciences

Faculty of life Sciences, Kumamoto University, Japan

Supervisors: Professor Nobuaki Tamamaki, Professor Hirohide Takebayashi

Thesis title: Mapping neuronal activity in the mouse brain by analyzing immediate early gene expression.

 

 

2002

 

Master of Pharmacy (Research)

Department of Pharmacy, Jahangirnagar University, Dhaka, Bangladesh

Thesis title: Market status of antibacterial agents and in vitro quality studies of amoxicillin trihydrate and its marketed capsule preparations.

 

 

2000

 

Bachelor of Pharmacy (Honors)

Department of Pharmacy, Jahangirnagar University, Dhaka, Bangladesh

2023-Nov-01 to date

Professor

Department of Pharmaceutical Sciences
School of Health and Life Sciences, North South University, Dhaka, Bangladesh

2018 to 2023

Associate Professor

Department of Pharmaceutical Sciences
School of Health and Life Sciences, North South University, Dhaka, Bangladesh

2013 to 2018

Assistant Professor (on leave from April 2015 to May 2017)

Department of Pharmaceutical Sciences
School of Health and Life Sciences, North South University, Dhaka, Bangladesh

2015 to 2017

Postdoctoral Researcher

Department of Neuroscience
University of Texas Southwestern Medical Centre Dallas, Texas, USA

Supervisor: Prof. Dr. Mark Henkemeyer

2013

Postdoctoral Researcher

Division of Neurobiology and Anatomy
Graduate School of Medical and Dental Sciences, Niigata University, Japan.

2009 to 2013

Doctoral Researcher

Department of Morphological Neural Science
Faculty of life sciences, Kumamoto University, Japan.

2007 to 2013

Junior Lecturer (on study leave from 2009 to 2013)

Department of Pharmacy, North South University, Dhaka.

2004 to 2006

Lecturer

Department of Pharmacy, Stamford University Bangladesh, Dhaka, Bangladesh

2002 to 2004

Executive

Division of International Marketing
The ACME Laboratories Limited, Dhaka, Bangladesh

  • Coordinated international marketing operations of pharmaceutical finished products for countries like Australia, China, India, Sri Lanka, and Pakistan.
  • Major duties involved identification and development of international markets for medical products, drafting business agreements, preparation of marketing plans, development of promotional materials, preparation of reports, participation in international meetings and exhibitions.
  • Biostatistics
  • Human Physiology
  • Pharmaceutical Analysis
  • Pharmacology
  • Pharmacotherapy

2024~

Life Member (ID: 0878), Japanese Universities Alumni Association

in Bangladesh (JUAAB)

2022~

Member, NSU IACUC

2021~2022

Canvas Coordinator, SHLS, NSU

2021~2022

Member, Canvas Rollout Steering Committee, NSU

2021~2022

Member, SHLS Core Research Facility Coordination Committee

2021

Member, NSU Pathology Lab Coordination Committee

2021

Member, NSU Brochure Committee

2020-2021

Member, Research Misconduct Investigation Committee (RMIC)

2020

Head, Graduate Defense Summer 2020 Committee

Department of Pharmaceutical Sciences

2020

Head, Graduate Defense Spring 2020 Committee

Department of Pharmaceutical Sciences

2019-2021

Research Coordinator, School of Health and Life Sciences

2017-2018

Coordinator, Spring 2018 Undergraduate Examination Committee

Department of Pharmaceutical Sciences

2017-2018

Graduate Program Coordinator (GPC)

Department of Pharmaceutical Sciences

2017

Coordinator, Academic Support Sub-committee

Department of Pharmaceutical Sciences

2014

Faculty advisor

North South University Pharmacy Club

Neuroscience

Neuroanatomy, Neurobiology, Neurodegenerative Disorders, Molecular Biology of Neuropathology, Biochemical Analysis of CNS Proteins, Genetics of Neurodevelopmental Disorders

 

  

Pharmacology of Plant Extracts

Biochemical, Behavioral, Histopathological, and Genetic Characterization of Plant Extracts using Rodent Models of Diabetes, Hypertension, and Neurodegenerative Disorders

 

  

Computational Drug Discovery

Deep Neural Network Machine Learning Models, Molecular Docking, and Molecular Dynamics Simulations for Drug Discovery