Center of Excellence in Higher Education
The First Private University in Bangladesh

Dr. Kazi Nadim Hasan

Full Time Faculty
Professor 

Ph.D., in Molecular Genetics, School of Medicine, Hirosaki University, Japan

Phone: +880-2-55668200 Ext: 1916
Email: nadim.hasan@northsouth.edu
Office:

Curriculum Vitae
 
 
 

 

 
 

Dr Nadim is the Professor of the Department of Biochemistry & Microbiology of School of Helath and Life Sciences at North South University. He was appointed as an Assistant Professor in the Department in  June 2009. Before that he had been associated with NSU  as Part-time Faculty in the rank of  Assistant Professor since January 2008. He had been promoted to Associate Professor on December, 2011. Dr Nadim served as the Chair of the Department from January, 2013  to May, 2014.  

Dr Nadim secured top position by achieving 1st Class both in my BS (Hons) and MSc in Biochemistry and Molecular Biology from the University of Dhaka. He also completed M. Phil in Biochemistry and Molecular Biology from the University of Dhaka. Before joining at NSU, he worked in the Department of Immunology, BIRDEM as a Research Officer for 13 years and his research works in BIRDEM resulted eleven International Publications in High Impact Peer Reviewed Journals. During his employment with BIRDEM, he went abroad to do his PhD.

Dr Nadim completed his PhD in the area of Human Molecular Genetics and Molecular Medicine from the Department of Laboratory Medicine, Internal Medicine, Hirosaki University School of Medicine, Hirosaki University, Japan. His research works during PhD tenure also resulted three publications in internationally reputed journals.

He conducted reserach works on the association of gene polymorhisms in life style related disorders, Gene expression profilling of platelets in enahnced aggregation and Micro RNA expression analysis in AVP stimulated hematopoetic progenitor cells. The title of his PhD dissertation was " Role of vasopressin V1a receptor (V1aR) gene polymorphism in essential hypertension, type 2 diabetes mellitus and platelet responsiveness to vasopressin".

 

Publications

  1. Md Asadulghani, Pawan Angra, Md Giasuddin, Md Latiful Bari, Md Shahidul Islam, Chandan Kumar Roy, Md Rakibul Islam, Zhahirul Islam, Kazi Nadim Hasan, Mohammad Aminul Islam, A.H.M. Nurun Nabi, Tasnim Farzana, Jamal Pasha Chowdhury, Munawar Sultana, Tania Mannan, Mohammad Hafizur Rahman, Abdul Jabbar Sikder, and Md Salimullah. Strengthening Biosafety and Biosecurity Status in Bangladesh: A Sustainable Approach. Applied Biosafety (APB). Jun 2020. https://doi.org/10.1177/1535676020930430
  2. Kazi N. Hasan, Abu Sufian, Ashish K. Mazumder, M. Abdul Khaleque, Mizanur Rahman & Sharif Akhteruzzaman. A Novel Pathogenic β-Thalassemia Mutation Identified at Codon 8 (HBB: c.27delG) in a Bangladeshi Family Acquired De Novo. Hemoglobin 2019, 43:3, 162-165, DOI: 10.1080/03630269.2019.1638797. https://doi.org/10.1080/03630269.2019.1638797
  3. Kazi Nadim Hasan, Abu Sufian, Ismail Hosen, Ashish Kumar Mazumder, Abdul Khaleque, Mizanur Rahman, Gias Uddin Ahsan and Sharif Akhteruzzaman. Beta-Thalassemia Caused by De novo Mutation in the beta-globin Gene Identified in Two Bangladeshi Families. J Blood Disord Transfus 2018; 9 (4): 408. Doi: 10.4172/2155-9864.1000408.
  4. Mukesh Jain, Sohidul Islam, A. S. M. Zisanur Rahman, Sharmin Akhtar, Kazi Nadim Hasan, Gias Uddin Ahsan, Abdul Khaleque, Maqsud Hossain. Molecular analysis of hemagglutinin, neuraminidase, matrix genes provide insight into the genetic diversity of seasonal H3N2 human influenza a viruses in Bangladesh during July–August, 2012. Virus Disease 2018; 29(44). doi: 10.1007/s13337-018-0431-y
  5. Kazi Nadim Hasan, Md Abdul Khaleque, Nahian Anjum Shejuti, Tanzila Wasi and Sohidul Islam. Prevalence of Hepatitis B Virus Seromarkers and Associated Risk Factors in Young Healthy Individuals in Bangladesh: Implications for Preventive Strategies. Hepat Mon. 2017; 17(6):e14245. doi: 10.5812/hepatmon.14245.
  6. Kazi Nadim Hasan, Tanzila Wasi, Nahian Anjum Shejuti, Aniqa Afzal, Sohidul Islam. COMPARATIVE EVALUATION OF TWO RAPID DIAGNOSTIC TEST DEVICES AND REAL-TIME PCR FOR THE DETECTION OF HEPATITIS B SURFACE ANTIGENS IN HUMAN PLASMA: IMPLICATIONS IN BLOOD DONATION SCREENING. J I T M M Proceedings, 2017; 6: 17 – 25. www.jitmm.com/proceeding
  7. Mashfiqul-Hasan, Hasanat MA , Nadim-Hasan K , Sandesh-Panthi , Yasmin-Aktar , Nusrat-Sultana , Sharmin-Jahan , Atiqur-Rahman M , Mazumder AK , Khaleque M A , Fariduddin M and Sharif-Akhteruzzaman. TCF7L2 gene rs7903146 polymorphism is observed in gestational diabetes mellitus in Bangladesh. Integr Obesity Diabetes, 2016; Volume 2(4): 250-254. doi: 10.15761/IOD.1000154
  8. M.A. Khaleque, C.A. Keya, K.N. Hasan, M.M. Hoque, Y. Inatsu, M.L. Bari. Use of cloves and cinnamon essential oil to inactivate Listeria monocytogenes in ground beef at freezing and refrigeration temperatures. LWT - Food Science and Technology 2016; 74: 219 – 223.
  9. Hasan, K. N., Khaleque, M. A., Majumder, A. K., Rahman, M. M., Akhteruzzaman, S. Identification of compound heterozygosity for rare beta-globin gene mutation, codon 15 (-T) with a common mutation IVS1-5 (G>C) by direct sequencing in a Bangladeshi patient. Biores comm. 2016; 2(2): 245 – 248.
  10. Ashish Kumar Majumder, Md. Abdul Khaleque, Kazi Nadim Hasan, Lamyah Sultana Meem and Sharif Akhteruzzaman. Two cases of Klinefelter Syndrome identified by quantitative fluorescence PCR (QF-PCR). Bioresearch Communications 2015; 1(1): 17 – 21.
  11. Atique FB, Ahmed KT, Asaduzzaman SM, Hasan KN. Effects of Gamma Irradiation on Bacterial Microflora Associated with Human Amniotic Membrane. Biomed Res Int. 2013; 2 013:586561. doi: 10.1155/2013/586561. Epub 2013 Aug 27.
  12. Kazi Nadim Hasan,  Fahmida Nasrin, M Abu Taher, Sharif Neaz, Sohidul Islam, Obaidur Rahman, Ishrat Jabeen, M Abdul Khaleque, Sharif Akhteruzzaman. Comparative Analysis of Hepatitis C Virus (HCV) RNA, Anti-HCV and Liver Transaminase Levels as Markers and Predictors of infectivity in HCV Infection. BJMS 2012; 18(2):120 – 125.
  13. Sohidul Islam, Lamyah Sultana Meem, Kazi Nadim Hasan, M Abdul Khaleque, Obaidur Rahman. Multidrug resistance of Pseudomonas aeruginosa Isolated from Burn Patients. BJMS 2012; 18(2):132 – 134 .
  14. Obaidur Rahman, Kazi Nadim Hasan, Abdul Khaleque, Ishrat Jabeen, Sohidul Islam. Dietary Intake of Urea from Puffed Rice (Muri) in Bangladesh. BJMS 2012; 18(1): 53 – 57.
  15. Hasan KN, Shoji M, Sugimoto K, Tsutaya S, Yasujima M. Role of vasopressin V1a receptor in hypertension, diabetes mellitus and platelet function: genetic polymorphism study. Hirosaki Med. J. 2007; 58: 35 – 52.
  16. Hasan KN, Shoji M, Sugimoto K, Tsutaya S, Matsuda E, Kudo R, Nakaji S, Suda T, Yasujima M. Association of novel promoter single nucleotide polymorphisms in vasopressin V1a receptor gene with essential hypertension in nonobese Japanese. J Hum Hypertens. 2007; 21(10):825-7.
  17. Zaid RB, Nargis M, Neelotpol S, Sayeed MA, Banu A, Shurovi S, Hassan KN, Salimullah M, Ali L, Azad Khan AK. Importance of acetylator phenotype in the identity of Asian populations. Hum Biol. 2007; 79(3):363-8.
  18. Hasan KN, Shoji M, Tsutaya S, Kudo R, Matsuda E, Saito J, Kimura T, Yasujima M. Study of V1a vasopressin receptor gene single nucleotide polymorphisms in platelet vasopressin responsiveness. J Clin Lab Anal. 2006; 20(3): 87-92.
  19. Golam Azam, Mak Rumi, Kazi Nadim Hasan, Ak Azad Khan. Family members at risk of hepatitis B due to horizontal transmission. J Gastro Hepat. 2006; 21:A16-A16
  20. Golam Azam, MAK Rumi, SMM Hassan, Kazi Nadim Hasan, AK Chowdhury, MS Hassan, AKA Khan. Cost-effectiveness of prevaccination screening for hepatitis B virus infection among hospital staff. J Gastro Hepat. 2004; 19(S):A856
  21. Aziz MM, Khan AY, Hasan KN, Azad Khan AK, Hassan MS. Comparison between IS6110 and MPB64 primers for the diagnosis of Mycobacterium tuberculosis in Bangladesh by polymerase chain reaction (PCR). Bangladesh Med Res Counc Bull. 2004; 30: 87-94.
  22. Hasanat MA, Rumi MA, Alam MN, Ahmed S, Hasan KN, Khan AY, Salimullah M, Mahtab H, Khan AK. Urinary iodine status and thyroid dysfunction: a Bangladesh perspective. Bangladesh Med Res Counc Bull. 2004; 30:16-24.
  23. Parvez MA, Hasan KN, Rumi MA, Ahmed S, Salimullah M, Tahera Y, Gomes DJ, Huq F, Hassan MS. PCR can help early diagnosis of pulmonary tuberculosis. Southeast Asian J Trop Med Public Health. 2003; 34: 147-53.
  24. Monowar Aziz, Kazi Nadim Hasan, AK Chowdhury, MAK Rumi, Y Tahera, Muhammad Abul Hasanat, M Elahi, MS Hassan. Leishmaniasis can be effectively diagnosed by PCR from peripheral blood. Immunology Letters 2003;87(1-3):179
  25. Aziz MM, Hasan KN, Hasanat MA, Siddiqui MA, Salimullah M, Chowdhury AK, Ahmed M, Alam MN, Hassan MS. Predominance of the DEN-3 genotype during the recent dengue outbreak in Bangladesh. Southeast Asian J Trop Med Public Health. 2002; 33:42-8.
  26. Hasan KN, Rumi MA, Hasanat MA, Azam MG, Ahmed S, Salam MA, Islam LN, Hassan MS. Chronic carriers of hepatitis B virus in Bangladesh: a comparative analysis of HBV-DNA, HBeAg/anti-HBe, and liver function tests. Southeast Asian J Trop Med Public Health. 2002; 33:110-7.
  27. Gibney L, Saquib N, Macaluso M, Hasan KN, Aziz MM, Khan AY, Choudhury P. STD in Bangladesh's trucking industry: prevalence and risk factors. Sex Transm Infect. 2002; 78: 31-6.
  28. Sayeed MA, Hassan MS, Hasan KN, Parvez MA, Khan AY, Salimullah M, Khanam PA, Mahtab H, Khan AK. Genetic background of diabetic and nondiabetic sibs in young Bangladeshis. Bangladesh Med Res Counc Bull. 2000; 26:69-74.
  29. Rumi MA, Siddiqui MA, Salam MA, Iqbal MR, Azam MG, Chowdhury AK, Khan AYM, Hasan KN, Hassan MS. Prevalence of infectious diseases and drug abuse among Bangladeshi workers. Southeast Asian J Trop Med Public Health. 2000; 31: 571-4.
  30. Hasanat MA, Rumi MA, Alam MN, Hasan KN, Salimullah M, Salam MA, Fariduddin M, Mahtab H, Khan AK. Status of antithyroid antibodies in Bangladesh. Postgrad Med J. 2000; 76: 345-9.
  31. Rumi MA, Begum K, Hassan MS, Hasan SM, Azam MG, Hasan KN, Shirin M, Khan AK. Detection of hepatitis B surface antigen in pregnant women attending a public hospital for delivery: implication for vaccination strategy in Bangladesh. Am J Trop Med Hyg. 1998; 59: 318-22.

 

 

Conference Papers

  • Abul Mueed Ibne Momen, Hossain Mohammad Nayeem Khan, Kazi Nadim Hasan*, Abu Sufian, Md Abul Khaleque, Ashish Kumar Majumde, Sharif Akhteruzzaman. Distribution of Hepatitis C virus genotypes and its association with viral load in Bangladeshi population. International Conference on Genomics, Nanotech & Bioengineering, May 2017, North South University, Bangladesh.
  • Abu sufian, Kazi Nadim Hasan*, Md. Abdul Khaleque, Ismail Hosen, Ashish Kumer Mazumder, and Sharif Akhteruzzaman. Beta Thalassemia Caused by De Novo Mutation in the Beta-Globin Gene Identified in Bangladeshi Population Sample. International Conference on Genomics, Nanotech & Bioengineering, May 2017, North South University, Bangladesh.
  • Nusrat Jahan Rouf, Muhammad Maqsud Hossain, Sohidul Islam, Md Abul Khaleque, Kazi Nadim Hasan*. Rapid Detection of SRY gene by conventional Polymerase Chain Reaction using in House Design Primers and Optimization: a cost effective approach. International Conference on Genomics, Nanotech & Bioengineering, May 2017, North South University, Bangladesh.
  • Kazi Nadim Hasan, Tanzila Wasi, Aniqa Afzal, Nahian Anjum Shejuti,Sohidul Islam. Comparative evaluation of two Rapid Tests Devices and Real-time PCR for the detection of hepatitis B surface antigen in human plasma: implications in blood donation screening. Joint International Tropical Medicine Meeting 2016 (JITMM 2016) Amari Watergate, Bangkok, Thailand.
  • Nahian Anjum Shejuti, Tanzila Wasi, Aniqa Afzal Esha, Sohidul Islam, Kazi Nadim Hasan*. Evaluation of immunological status, acquisition risK factors and awareness regarding hepatitis B Virus (HBV) infection among young healthy individuals in Bangladesh Joint International Tropical Medicine Meeting 2016 (JITMM 2016), Amari Watergate, Bangkok, Thailand.
  • National conference on Biochemistry and Molecular Biology for Life Sciences 2016, held in University of Dhaka, Bangladesh
  • Khaleque, C.A. Keya, K.Nadim Hasan, M.M. Hoque, Y. Inatsu, M.L. Bari. Use of cloves and cinnamon essential oil to inactivate Listeria monocytogenes in ground beef at freezing and refrigeration temperatures. 3rd Asian Food Safety & Security Association Conference September 2016, KIIT University, Bhubaneswar, India.
  • 10th Meeting of Hirosaki International Forum of Medical Science, 2006 held in Hirosaki, Japan
  • 21st Scientific Meeting of the International Society of Hypertension, 2006 held in Fukuoka, Japan.
  • 53rd  National Congress of the Japanese Society of Laboratory Medicine, 2006 held in Hirosaki, Japan.
  • 52nd  National Congress of the Japanese Society of Laboratory Medicine, 2005 held in Fukuoka, Japan.
  • 51st National Congress of the Japanese Society of Laboratory Medicine, 2004 held in Tokyo, 

Japan.

  • Tohoku Society of Laboratory Medicine, 2004 held Hirosaki, Japan
  • Tohoku Society of Laboratory Medicine, 2003 held Hirosaki, Japan
  • 37th Annual Meeting of the European Association for the Study of the Liver, 2002 held in Madrid,    Spain.
  • 11th International Congress of Immunology, 2001 held in Stockholm, Sweden
  • 10th International Congress of Immunology, 1998 held in New Delhi, India.          

Awards and Honours

  • NSU Research Grants (CTRG) for 3 cycles
  • External Research Grants: Ministry of Science & Technology, Republic of Bangladesh. Special Allocation Grant 2018-19
  • Rotary Yoneyama Memorial Foundation Scholarship, Doctoral Fellowship, Hirosaki University, 2005 – 2007
  • Hirosaki City Scholarship, Hirosaki University, 2004 – 2005
  • Honours Scholarship, Japanese Government (Monbukagakusho) Doctoral student Fellowship, Hirosaki University, 2003 – 2004

Hirosaki University School of Medicine, Hirosaki University, Japan

  • PhD, Internal Medicine (Laboratory Medicine, Human Molecular Genetics)        2003 – 2007

University of Dhaka, Bangladesh

  • Master of Philosophy (M.Phil), Biochemistry and Molecular Biology                    2000
  • Master of Science (M.Sc), Biochemistry and Molecular Biology                          1995

    (First Class, Third Position)
                                                                               

  • Bachelor of Science (B.Sc), Biochemistry and Molecular Biology                        1992

     (First Class, Fourth Position)                                                                             

1) Professor, Department of Biology & Chemistry, North South University
                                                                                                           February 4, 2016 - till now 

2) Associate Professor, Dept. of Biology & Chemistry, North South University

                                                                                                            December 26, 2011 – February 3, 2016

Chairman, Dept. of Biology & Chemistry, North South University

January 01, 2013 – May 18, 2014

3) Assistant Professor, Dept. of Biology & Chemistry, North South University                

                                                                                                            Summer 2009 – Fall 2011


4) Assistant Professor, Dept. of Biology & Chemistry, North South University   
                                                                                                            January,2008 to May, 2009 


Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM)-

Department of Immunology

As Research Officer

Before PhD: 1996 – 2003

As Post Doctoral Research Fellow after PhD: 2007-2009

Research and Professional experiences

Department of Biochemistry and Microbiology, School of Life Sciences, North South University

Ongoing research involving

  • Infectious disease immunology and molecular biology with different diagnostic approaches on hepatitis, dengue and pulmonary tuberculosis.
  • Association of candidate gene polymorphisms with life style related disorders.
  • Nutritional assessment of Foods; Assessment of food adulteration
  • Mechanism of Antibiotic Resistance
  • Enzymes as industrial catalysts that are capable of producing useful chemicals or eliminate dangerous ones

Hirosaki University School of Medicine, Japan; PhD Research   

  • Role of vasopressin V1a receptor (V1aR) gene polymorphism in essential hypertension, type 2 diabetes mellitus and platelet responsiveness to vasopressin.

Also involved in-

  • Gene expression profiling of platelets from individual with enhanced response to AVP (AVP responder) and individual with low response to AVP (AVP non-responder) by oligoarray using AceGene® Human Oligo Chip 30K 1 Chip Version.  
  • Platelet V1a receptor mRNA expression in healthy subjects defined by the four SNPs of V1aR gene.
  • Micro RNA (miRNA) expression analysis in AVP stimulated CD34+ hematopoetic progenitor cells.           

  University of Dhaka, Bangladesh; M.Phil thesis

  • Evaluation of chronic hepatitis B virus infection using serum DNA level, serological markers and liver function tests.

  University of Dhaka, Bangladesh; M.Sc thesis

  • Effect of goitrogens (KSCN and AITC) on growth and development of the rat brain.

   Department of Immunology, BIRDEM; Research (Employment tenure)

  • Infectious disease immunology and molecular biology with different diagnostic approaches on hepatitis, pulmonary tuberculosis and sexually transmitted diseases (STD).
  • Genetic backgrounds of diabetic and non-diabetic sibs in young Bangladeshis

Department of Immunology, BIRDEM (Employment tenure)

  • Involved in establishing molecular based diagnosis of hepatitis B, C, M tuberculosis; Molecular based tissue typing (HLA A, B, DR, DQ genotyping).
  • Supervision of medical technologists involved in the diagnostic serology, immunochemistry
  • Taught M.Phil students of the department

Part-time Faculty in the Department of Biochemistry and Microbiology, School of Health and Life Sciences, North South University                    Spring 2008 – Spring 2009

  • Courses taught: Biophysical Chemistry, Proteins and Enzymes, Immunology

Assistant Professor, Department of Biochemistry and Microbiology, School of Health and Life Sciences, North South University                    Summer 2009 – Fall 2011

  • Courses taught: Biophysical Chemistry, Proteins and Enzymes, Immunology I, Immunology II, Genes and diseases, Biology I, Laboratory Courses: Biochemistry, Immunology, Molecular biology, Molecular Diagnostics
  • Supervised research projects of undergraduate students and dissertations of graduate students

 Associate Professor, Department of Biochemistry and Microbiology, North South University                                                                        December 26, 2011 – February 03, 2016

  • Courses taught: Biophysical Chemistry, Proteins and Enzymes, Immunology I, Immunology II, Genes and diseases, Biology I, Laboratory Courses: Biochemistry, Immunology, Molecular biology, Molecular Diagnostics
  • Supervised research projects of undergraduate students and dissertations of graduate students

 

Department of Laboratory Medicine, Hirosaki University School of Medicine            2003 – 2007

  • Taught MD students of School of Medicine, Supervised research projects of MD students enrolled in the Department.
  • Member, Japanese Society of Laboratory Medicine, Japan
  • Member, Graduate Biochemists Association, Bangladesh
  • Member, Bangladesh Society for Biochemistry and Molecular Biology, Bangladesh.
  • Member, Japanese Universities Alumni Association in Bangladesh (JUAAB) , Bangladesh
  • Advisor, Bangladesh Biosafety & Biosecurity Association (BBBA), Dhaka

Human Molecular Genetics, Molecular Medicine, Molecular Diagnostics, Infectious Disease Immunology and Epidemiology.

Presently, research is directed to

  • Projects of North South University on Complete genome sequencing of SARS-CoV-2 circulating in Bangladesh, comprehensive variant and phylogenetic analysis approach.
  • Study of the SARS-CoV-2 derived Peptidome Presentation by HLA Class I: A Random Forest Approach
  • Role of variants of drug metabolizing genes of human to determine optimum dose of the drug for the individual, a vital area of personalized medicine.
  • Molecular Diagnostics approaches of infectious diseases like hepatitis, pulmonary tuberculosis and sexually transmitted diseases (STD) and genetic disorders: development and optimization of protocols.
  • Determination of hepatitis C virus genotypes and subtypes in Bangladesh by Direct Sequencing analysis of 5′ -UTR of HCV genome.
  • Identification and Comparison of Hepatitis C Virus (HCV) Genotypes by Next    Generation Sequencing (NGS) and Sanger Sequencing.
  • Molecular Diagnostics approaches of genetic disorders like beta-thalassemia by direct sequencing prenatal and postnatal: identifying rare, novel mutation inheritance in Bangladeshi population
  • Identification and analysis of mutation inheritance causing genetic disorders by Next Generation Sequencing
  • Finding the association of candidate gene polymorphisms with life style related disorders like diabetes, hypertension.
  • Infectious disease Immunology and Epidemiology.
  • Molecular Assessment of Food Adulteration and Food Pathogen Detection